Studies of the molecular mechanism in the transport and the accumulation of caffeine
| Project/Area Number |
22603004
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
ケミカルバイオロジー
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| Research Institution | Ochanomizu University |
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Principal Investigator |
KATO Misako お茶の水女子大学, 大学院・人間文化創成科学研究科, 教授 (60272738)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | カフェイン / テオブロミン / チャ / ツバキ科植物 / プリンアルカロイド / メチルトランスフェラーゼ |
|---|
| Research Abstract |
Caffeine is a purine alkaloid that is present in high concentration in Camellia sinensis. Twenty motif B’ methyltransferase genes were isolated from plants Theaceae as the homologous gene to caffeine synthase. The overall structure of these methyltransferasesand the spatial structure of the substrate binding sites were predicted by comparative modeling. Moreover, green callus containing caffeine was induced from the tea plant as the model experiment system to investigate the transport and the accumulation of caffeine.
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Report
(4 results)
Research Products
(8 results)
