Studies on the tissue repair capability of the epithelia of gray short-tailed opossums at their immature stage
| Project/Area Number |
22657018
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphology/Structure
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| Research Institution | Shimane University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | ハイイロジネズミオポッサム / 有袋類 / 創傷治癒 / 未成熟期 / 皮膚 / 表皮 / 創閉鎖 / ケラチン / 末成熟期 |
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| Research Abstract |
Previous studies show that, in placental mammals such as rats, the mode of wound healing transits from the fetal-type to adult-type during the fetal stage. This study aimed at morphological characterization in vivo as well as in vitro of the wound repair capability of the skin of a marsupial gray short -tailed opossum (Monodelphis domestica) which is known to be born in a very "premature" state, and revealed that the mode of healing depended on the events chosen as the evaluation criteria. Further analyses on the possible marsupial uniqueness, with respect to the heterochrony that one-day neonates already have a cornified epidermis, are promising for elucidation of the establishment of tissue rapair ability in marsupials.
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Report
(4 results)
Research Products
(8 results)
