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Development of therapies for metastatic liver cancer with liver cells induced hibernation

Research Project

Project/Area Number 22659241
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionTohoku University

Principal Investigator

KATAYOSE Yu  東北大学, 大学院・医学系研究科, 准教授 (20302151)

Co-Investigator(Kenkyū-buntansha) NAKAGAWA Kei  東北大学, 大学院・医学系研究科, 助教 (20542294)
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,230,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,800,000 (Direct Cost: ¥1,800,000)
Keywords転移性肝癌 / 大腸癌 / 肝細胞癌 / 冬眠
Research Abstract

Hibernating state is considered to be similar as Cancer stem cell from the concept of G0, using TFK-1, HuCCT1 biliary tract cancer cell lines. We analyzed using CD133, CD44, EpCAM of Cancer stem cell markers. CD133 in bile duct cancer is suggested as a marker of hibernating state.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (1 results)

All 2011

All Presentation (1 results)

  • [Presentation] CD133は胆管癌における腫瘍増殖に関係する(CD133 is related to tumorigenicity in cholangiocarcinoma)2011

    • Author(s)
      北村洋、片寄友
    • Organizer
      日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Related Report
      2011 Final Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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