| Project/Area Number |
22659305
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KITAMURA Ken 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (90010470)
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| Co-Investigator(Kenkyū-buntansha) |
NOGUCHI Yoshihiro 東京医科歯科大学, 医学部附属病院, 講師 (50282752)
KIMURA Yurika 東京都健康長寿医療センター, 研究所, 研究院 (40450564)
SAWABE Motoji 東京医科歯科大学, 医学部保健衛生学科, 教授 (30196331)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,280,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | 遺伝子 / 医療・福祉 / 神経科学 / 脳・神経 |
|---|
| Research Abstract |
Immunohistochemical study of cochlin demonstrated increased rate of positive area in the spiral ligament of the basal turn of the cochlea of the subjects at the age of older than 90 years than that of the age from 65 to 75 years. We succeeded to extract mRNA of COCH and SLC26A5 from archival formalin fixed paraffin embedded human cochlear cells by laser microdissection.
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