| Project/Area Number |
22659313
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUDA Akira 順天堂大学, 医学部, 准教授 (00312348)
海老原 伸行 順天堂大学, 医学部, 先任准教授 (20255699)
|
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| Co-Investigator(Renkei-kenkyūsha) |
EBIHARA Nobuyuki 順天堂大学, 医学部, 先任准教授 (20255699)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,190,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | 白内障 / 緑内障 / ステロイド / PAI-1 / 遺伝子多型 |
|---|
| Research Abstract |
We investigated the molecular pathology of atopic cataracts and found essential roles of PAI-1, an downstream molecule of IFN-γ, for the cataractgenesis. We also reported clinical and pathological features of atopic glaucoma as new clinical entity. We published these findings in an academic journal.
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