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Vascularization of three-dimensional complex liver tissues byregulation of interstitial flow

Research Project

Project/Area Number 22680037
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionKeio University

Principal Investigator

SUDO Ryo  慶應義塾大学, 理工学部, 准教授 (20407141)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Keywordsマイクロ流体デバイス / 肝臓 / 血管 / 生物・生体工学 / マイクロ・ナノデバイス / 細胞・組織
Research Abstract

There is a demand to reconstruct three-dimensional (3D) complex organs inrecent regenerative medicine. In particular, it is important to reconstruct 3D complex tissues includingmicrovascular networks. In this study, we investigated a technology to vascula

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (80 results)

All 2013 2012 2011 2010 Other

All Journal Article (19 results) (of which Peer Reviewed: 17 results) Presentation (59 results) Remarks (2 results)

  • [Journal Article] A three-dimensional microfluidic tumor cell migration assay to screen the effect of anti-migratory drugs and interstitial flow2013

    • Author(s)
      Johann Kalchman
    • Journal Title

      Microfluidics and Nanofluidics

      Volume: 掲載確定

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction of hepatic stellate cell-incorporated liver capillary structures in small hepatocyte tri-culture using microporous membranes2013

    • Author(s)
      Junichi Kasuya
    • Journal Title

      Journal of Tissue Engineering and Regenerative Medicine

      Volume: 掲載確定

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Steady and pulsatile shear stress induce differenct three-dimensional endothelial networks through pseudopodium formation2013

    • Author(s)
      Yoshinori Abe
    • Journal Title

      Journal of Biorheology

      Volume: 掲載確定

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The stabilization effect of mesenchymal stem cells on the formation of microvascular networks in a microfluidic device2013

    • Author(s)
      Kyoko Yamamoto
    • Journal Title

      Journal of Biomechanical Science and Engineering

      Volume: 掲載確定

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microfluidic assay for simultaneous cultureof multiple cell types on surfaces or withinhydrogels2012

    • Author(s)
      Yoojin Shin, Sewoon Han, Jessie S. Jeon,Kyoko Yamamoto, Ioannis K. Zervantonakis,Ryo Sudo, Roger D. Kamm, Seok Chung
    • Journal Title

      Nature Protocols

      Volume: 7 Pages: 1247-1259

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spatio-temporal control of hepatic stellatecell-endothelial cell interactions forreconstruction of liver sinusoids in vitro2012

    • Author(s)
      Junichi Kasuya, Ryo Sudo, Toshihiro Mitaka,Mariko Ikeda, Kazuo Tanishita
    • Journal Title

      Tissue Engineering Part A

      Volume: 18 Pages: 1045-1056

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spatio-temporal control of hepatic stellate cell-endothelial cell interactions for reconstruction of liver sinusoids in vitro2012

    • Author(s)
      Junichi Kasuya
    • Journal Title

      Tissue Engineering Part A

      Volume: 18 Pages: 1045-1056

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels2012

    • Author(s)
      Yoojin Shin
    • Journal Title

      Nature Protocols

      Volume: 7 Pages: 1247-1259

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction of 3D stacked hepatocyte tissues using degradable, microporous poly(D,L-lactide-co-glycolide) membranes2012

    • Author(s)
      Junichi Kasuya, Ryo Sudo, Ryu Tamogami, Genta Masuda, Toshihiro Mitaka, Mariko Ikeda, Kazuo Tanishita
    • Journal Title

      Biomaterials

      Volume: 33 Pages: 2693-2700

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients2011

    • Author(s)
      Yoojin Shin, Jessie Jeon, Sewoon Han, Gi-Seok Jung, Sehyun Shin, Sang-Hoon Lee, Ryo Sudo, Roger Kamm, Seok Chung
    • Journal Title

      Lab on a Chip

      Volume: 11 Pages: 2175-2181

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 流れ刺激による3次元毛細血管ネットワーク形成2011

    • Author(s)
      須藤亮、谷下一夫
    • Journal Title

      細胞

      Volume: 43 Pages: 334-338

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Hepatic Stellate Cell-Mediated Three-Dimensional Hepatocyte and Endothelial Cell Triculture Model2011

    • Author(s)
      Junichi Kasuya, Ryo Sudo, Toshihiro Mitaka, Mariko Ikeda, Kazuo Tanishita
    • Journal Title

      Tissue Engineering Part A

      Volume: Vol.17 Pages: 361-370

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments2011

    • Author(s)
      Ioannis Zervantonakis, Chandrasekhar Kothapalli, Seok Chung, Ryo Sudo, Roger Kamm
    • Journal Title

      Biomicrofluidics

      Volume: 5

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] せん断応力に依存した血管内皮細胞の3次元ネットワーク形成2010

    • Author(s)
      阿部順紀、須藤亮, 池田満里子、谷下一夫
    • Journal Title

      日本機械学会論文集(B編)

      Volume: 76巻 Pages: 51-57

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 力学的刺激による血管形成のバイオニソクデザイン2010

    • Author(s)
      須藤亮、谷下一夫
    • Journal Title

      血管医学

      Volume: Vol.11 Pages: 55-61

    • Related Report
      2010 Annual Research Report
  • [Journal Article] The stabilization effectof mesenchymal stem cells on the formationof microvascular networks in a microfluidicdevice.

    • Author(s)
      Kyoko Yamamoto, Kohei Tanimura, YoMabuchi, Yumi Matsuzaki, Seok Chung,Roger D. Kamm, Mariko Ikeda, KazuoTanishita, Ryo Sudo
    • Journal Title

      Journal of Biomechanical Scienceand Engineering

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Steady and pulsatile shearstress induce differenct three-dimensionalendothelial networks through pseudopodiumformation

    • Author(s)
      Yoshinori Abe, Ryo Sudo, Mariko Ikeda,Kazuo Tanishita.
    • Journal Title

      Journal of Biorheology

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction of hepatic stellatecell-incorporated liver capillary structures in small hepatocyte tri-culture usingmicroporous membranes

    • Author(s)
      Junichi Kasuya, Ryo Sudo, Genta Masuda,Toshihiro Mitaka, Mariko Ikeda, KazuoTanishita
    • Journal Title

      Journal of TissueEngineering and Regenerative Medicine

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A three-dimensional microfluidic tumor cellmigration assay to screen the effect ofanti-migratory drugs and interstitial flow

    • Author(s)
      Johann Kalchman, Shingo Fujioka, SeokChung, Yamato Kikkawa, Toshihiro Mitaka,Roger D. Kamm, Kazuo Tanishita, Ryo Sudo
    • Journal Title

      Microfluidics and Nanofluidics

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] 安定化毛細血管の再生における血管内皮細胞と間葉系幹細胞の相互作用2013

    • Author(s)
      山本 興子
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      神奈川
    • Year and Date
      2013-03-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 血管内皮細胞と間葉系幹細胞の相互作用による毛細血管安定化の検討2013

    • Author(s)
      山本 興子
    • Organizer
      日本機械学会第25回バイオエンジニアリング講演会
    • Place of Presentation
      茨城
    • Year and Date
      2013-01-10
    • Related Report
      2012 Final Research Report
  • [Presentation] マウス背側皮膚窓による培養小型肝細胞組織移植に伴う血管新生の観察2013

    • Author(s)
      若杉 美樹
    • Organizer
      日本機械学会第25回バイオエンジニアリング講演会
    • Place of Presentation
      茨城
    • Year and Date
      2013-01-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 生体工学的手法による微小血管構築制御2013

    • Author(s)
      須藤 亮
    • Organizer
      日本機械学会 第25回 バイオエンジニアリング講演会
    • Place of Presentation
      茨城
    • Year and Date
      2013-01-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Three-dimensional liver cancercell migration assay under interstitial flow ina microfluidic system2012

    • Author(s)
      Ryo Sudo
    • Organizer
      1^<st>Annual IEEEEMBS Micro and Nanotechnology inMedicine Conference
    • Place of Presentation
      Ka'anapali, USA
    • Year and Date
      2012-12-04
    • Related Report
      2012 Final Research Report
  • [Presentation] 血管内皮細胞の 3 次元ネットワーク形成に及ぼす間質流の影響2012

    • Author(s)
      阿部順紀
    • Organizer
      日本生体医工学会関東支部若手研究者発表会
    • Place of Presentation
      東京
    • Year and Date
      2012-11-17
    • Related Report
      2012 Final Research Report
  • [Presentation] マウス背側皮膚窓への培養肝細胞組織移植による血管新生観察と組織酸素分圧測定2012

    • Author(s)
      若杉 美樹
    • Organizer
      第16回 酸素ダイナミクス研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-09-29
    • Related Report
      2012 Final Research Report
  • [Presentation] Construction of functionalex-vivo liver tissues withpericytes-incorporated microvessels usingmicroporous membranes2012

    • Author(s)
      Junichi Kasuya
    • Organizer
      3^<rd>TERMIS WorldCongress
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2012-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Quantitative analysis ofinteractions between capillary networks andhepatocyte tissues in a microfluidic platform2012

    • Author(s)
      Ryo Sudo
    • Organizer
      3^<rd>TERMIS WorldCongress
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2012-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] 小型肝細胞-星細胞-血管内皮細胞共培養モデルにおける肝類洞様構造の再構築と肝細胞機能発現2012

    • Author(s)
      須藤 亮
    • Organizer
      第19回 肝細胞研究会
    • Place of Presentation
      北海道
    • Year and Date
      2012-06-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝細胞との共培養が血管内皮細胞の三次元ネットワーク形成に与える影響2012

    • Author(s)
      須藤 亮
    • Place of Presentation
      神奈川
    • Year and Date
      2012-06-12
    • Related Report
      2012 Final Research Report
  • [Presentation] 生体外における肝臓再生への工学的アプローチ2012

    • Author(s)
      須藤 亮
    • Organizer
      分野横断型医工学研究プラットフォーム BASIC 特別講演会
    • Place of Presentation
      宮城
    • Year and Date
      2012-02-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 生体外における肝臓再生への工学的アプローチ2012

    • Author(s)
      須藤亮
    • Organizer
      分野横断型医工学研究プラットフォームBASIC特別講演会
    • Place of Presentation
      東北大学(宮城県)(招待講演)
    • Year and Date
      2012-02-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスを用いた三次元組織再生への工学的アプローチ2012

    • Author(s)
      須藤 亮
    • Organizer
      バイオフィジオロジー研究会
    • Place of Presentation
      京都
    • Year and Date
      2012-02-25
    • Related Report
      2012 Final Research Report
  • [Presentation] マイクロ流体デバイスを用いた三次元組織再生への工学的アプローチ2012

    • Author(s)
      須藤亮
    • Organizer
      バイオフィジオロジー研究会
    • Place of Presentation
      ホテル京都京阪(京都府)(招待講演)
    • Year and Date
      2012-02-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Microfluidic culture models forinvestigating normal and cancer cellbehaviors2012

    • Author(s)
      Ryo Sudo
    • Organizer
      バイオメカニクス懇話会
    • Place of Presentation
      北海道
    • Year and Date
      2012-01-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Microfluidic culture models for investigating normal and cancer cell behaviors2012

    • Author(s)
      Ryo Sudo
    • Organizer
      バイオメカニクス懇話会
    • Place of Presentation
      北海道大学(北海道)(招待講演)
    • Year and Date
      2012-01-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスを用いた肝細胞組織-毛細血管ネットワーク間相互作用の解析2012

    • Author(s)
      辻知宏
    • Organizer
      日本機械学会第24回バイオエンジニアリング講演会
    • Place of Presentation
      大阪大学(大阪府)
    • Year and Date
      2012-01-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 間葉系幹細胞と血管内皮細胞の共培養による毛細血管ネットワークの構築2012

    • Author(s)
      須藤亮
    • Organizer
      日本機械学会第24回バイオエンジニアリング講演会
    • Place of Presentation
      大阪大学(大阪府)
    • Year and Date
      2012-01-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスを用いた生体外培養モデルの有用性2011

    • Author(s)
      須藤亮
    • Organizer
      日本コンピュータ外科学会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Year and Date
      2011-11-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Quantitative analysis of theinteractions between 3D hepatocyte tissueand capillary networks in a microfluidicplatform2011

    • Author(s)
      Tomohiro Tsuji
    • Organizer
      MicroTAS 2011
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2011-10-03
    • Related Report
      2012 Final Research Report
  • [Presentation] Quantitative analysis of the interactions between 3D hepatocyte tissue and capillary networks in a microfluidic platform2011

    • Author(s)
      Tomohiro Tsuji
    • Organizer
      MicroTAS 2011
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2011-10-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Dorsal skinfold chamberを用いた生体内肝臓組織形成の可視化に関する検討2011

    • Author(s)
      若杉美樹
    • Organizer
      日本バイオイメージング学会
    • Place of Presentation
      千歳科学技術大学(北海道)
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Spatio-temporal control of hepatic stellate cell-endothelial cell interactions for reconstruction of vascularized liver constructs in vitro2011

    • Author(s)
      Junichi Kasuya
    • Organizer
      Tissue Engineering and Regenerative Medicine International Society Asia-Pacific Chapter Meeting
    • Place of Presentation
      Singapore
    • Year and Date
      2011-08-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスを用いた三次元組織の再生2011

    • Author(s)
      須藤亮
    • Organizer
      東京大学マイクロ・ナノ多機能デバイス研究ネットワーク第3回シンポジウム
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Year and Date
      2011-07-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] 星細胞-血管内皮細胞間接触による血管形態形成の制御2011

    • Author(s)
      粕谷淳一
    • Organizer
      肝細胞研究会
    • Place of Presentation
      東京ガーデンパレス(東京都)
    • Year and Date
      2011-06-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスにおける肝細胞組織-血管ネットワーク間相互作用の定量的解析2011

    • Author(s)
      辻知宏
    • Organizer
      肝細胞研究会
    • Place of Presentation
      東京ガーデンパレス(東京都)
    • Year and Date
      2011-06-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 乳酸-グリコール酸共重合体薄膜を用いた小型肝細胞,星細胞及び血管内皮細胞の三次元複合組織の再構築2011

    • Author(s)
      益田源太
    • Organizer
      肝細胞研究会
    • Place of Presentation
      東京ガーデンパレス(東京都)
    • Year and Date
      2011-06-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Dorsal skinfold chamberを用いた生体内肝臓組織形成の可視化に関する検討2011

    • Author(s)
      若杉美樹
    • Organizer
      日本バイオレオロジー学会
    • Place of Presentation
      関西大学(大阪府)
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスにおける血管内皮細胞-間葉系幹細胞共培養系の構築2011

    • Author(s)
      山本興子
    • Organizer
      日本バイオレオロジー学会
    • Place of Presentation
      関西大学(大阪府)
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Quantitative analysis of the interactions between 3D hepatocyte tissues and capillary networks in the microfluidic platform2011

    • Author(s)
      Tomohiro Tsuji
    • Organizer
      日本生体医工学会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2011-04-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロ流体デバイスにおける血管内皮細胞-肝細胞組織間相互作用の定量的解析-2011

    • Author(s)
      辻知宏
    • Organizer
      日本再生医療学会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2011-03-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] A bioengineering approach toliver tissue engineering2010

    • Author(s)
      Ryo Sudo
    • Organizer
      BiofrontierSymposium 2010
    • Place of Presentation
      石川
    • Year and Date
      2010-11-11
    • Related Report
      2012 Final Research Report
  • [Presentation] A Bioengineering Approach to Liver Tissue Engineering2010

    • Author(s)
      Ryo Sudo
    • Organizer
      Biofrontier Syposium 2010
    • Place of Presentation
      IT Business Plaza Musashi(石川県)
    • Year and Date
      2010-11-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロ流体デバイスにおける毛細血管の再生2010

    • Author(s)
      須藤亮
    • Organizer
      酸素ダイナミクス研究会
    • Place of Presentation
      島津製作所東京支社イベントホール(東京都)
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hepatocyte-endothelial cellinteractions monitored in a microfluidicdevice2010

    • Author(s)
      Ryo Sudo
    • Organizer
      World Congress of Biomechanics2010
    • Place of Presentation
      Suntec ConventionCentre, Singapore
    • Year and Date
      2010-08-01
    • Related Report
      2012 Final Research Report
  • [Presentation] Hepatocyte-endothelial cell interactions monitored in a microfluidic device2010

    • Author(s)
      Ryo Sudo
    • Organizer
      World Congress of Biomechanics 2010
    • Place of Presentation
      Suntec Convention Centre (Singapore)
    • Year and Date
      2010-08-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hepatic Stellate Cell-mediated Three-dimensional Hepatocyte and Endothelial Cell Tri-culture Model for a Physiological Liver Experimental Model2010

    • Author(s)
      Junichi Kasuya
    • Organizer
      World Congress of Biomcchanics 2010
    • Place of Presentation
      Suntec Convention Centre (Singapore)
    • Year and Date
      2010-08-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] A New Door for Tissue Engineering Opened by Microfluidic Devices2010

    • Author(s)
      Ryo Sudo
    • Organizer
      日本生体医工学会
    • Place of Presentation
      大阪国際交流センター(大阪府)
    • Year and Date
      2010-06-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of pulsatile flow on three-dimensional microvessel network formation2010

    • Author(s)
      阿部順紀
    • Organizer
      日本生体医工学会
    • Place of Presentation
      大阪国際交流センター(大阪府)
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 3D Stacked-up structure by rat small hepatocytes and endothelial cells on PLGA (poly lactic-glycolic acid) membrane2010

    • Author(s)
      益田源太
    • Organizer
      日本生体医工学会
    • Place of Presentation
      大阪国際交流センター(大阪府)
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hepatic stellate cell-mediated three-dimensional hepatocyte and endothelial cell tri-culture model2010

    • Author(s)
      粕谷淳一
    • Organizer
      日本生体医工学会
    • Place of Presentation
      大阪国際交流センター(大阪府)
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血管内皮細胞の3次元ネットワーク形成に及ぼす定常及び拍動せん断応力の影響2010

    • Author(s)
      阿部順紀
    • Organizer
      日本バイオレオロジー学会
    • Place of Presentation
      理化学研究所(埼玉県)
    • Year and Date
      2010-06-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロ流体デバイスによる微小細胞環境の制御と多細胞組織化の検討2010

    • Author(s)
      須藤亮
    • Organizer
      日本バイオレオロジー学会
    • Place of Presentation
      理化学研究所(埼玉県)
    • Year and Date
      2010-06-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] A 3D microfluidic cancer cell migration assay to screen the effect of anti-migratory drugs and interstitial flow

    • Author(s)
      Johann Kalchman
    • Organizer
      第51回 日本生体医工学会大会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 血管透過性による毛細血管ネットワークの再形成プロセスの評価

    • Author(s)
      谷村耕平
    • Organizer
      第35回 日本バイオレオロジー学会年会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター(新潟県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 肝細胞との共培養が血管内皮細胞の三次元ネットワーク形成に与える影響

    • Author(s)
      須藤亮
    • Organizer
      第11回 日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 背側皮膚窓を用いた三次元移植肝細胞組織の細胞動態観察

    • Author(s)
      若杉美樹
    • Organizer
      第11回 日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 血管内皮細胞-間葉系幹細胞共培養系における細胞間相互作用の検討

    • Author(s)
      山本興子
    • Organizer
      第11回 日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 小型肝細胞-星細胞-血管内皮細胞共培養モデルにおける肝類洞様構造の再構築と肝細胞機能発現

    • Author(s)
      須藤亮
    • Organizer
      第19回 肝細胞研究会
    • Place of Presentation
      札幌医科大学(北海道)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Quantitative analysis of interactions between capillary networks and hepatocyte tissues in a microfluidic platform

    • Author(s)
      Ryo Sudo
    • Organizer
      3rd TERMIS World Congress
    • Place of Presentation
      Vienna (Austria)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Construction of functional ex-vivo liver tissues with pericytes-incorporated microvessels using microporous membranes

    • Author(s)
      Junichi Kasuya
    • Organizer
      3rd TERMIS World Congress
    • Place of Presentation
      Vienna (Austria)
    • Related Report
      2012 Annual Research Report
  • [Presentation] マウス背側皮膚窓への培養肝細胞組織移植による血管新生観察と組織酸素分圧測定

    • Author(s)
      若杉美樹
    • Organizer
      第16回 酸素ダイナミクス研究会
    • Place of Presentation
      島津製作所東京支社イベントホール(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 血管内皮細胞の3次元ネットワーク形成に及ぼす間質流の影響

    • Author(s)
      阿部順紀
    • Organizer
      日本生体医工学会関東支部若手研究者発表会
    • Place of Presentation
      東京都市大学世田谷キャンパス(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Three-dimensional liver cancer cell migration assay under interstitial flow in a microfluidic system

    • Author(s)
      Ryo Sudo
    • Organizer
      1st Annual IEEE EMBS Micro and Nanotechnology in Medicine Conference
    • Place of Presentation
      Ka’anapali (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生体工学的手法による微小血管構築制御

    • Author(s)
      須藤亮
    • Organizer
      日本機械学会 第25回 バイオエンジニアリング講演会
    • Place of Presentation
      産業技術総合研究所つくばセンター(茨城県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] マウス背側皮膚窓による培養小型肝細胞組織移植に伴う血管新生の観察

    • Author(s)
      若杉美樹
    • Organizer
      日本機械学会 第25回 バイオエンジニアリング講演会
    • Place of Presentation
      産業技術総合研究所つくばセンター(茨城県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 血管内皮細胞と間葉系幹細胞の相互作用による毛細血管安定化の検討

    • Author(s)
      山本興子
    • Organizer
      日本機械学会 第25回 バイオエンジニアリング講演会
    • Place of Presentation
      産業技術総合研究所つくばセンター(茨城県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 安定化毛細血管の再生における血管内皮細胞と間葉系幹細胞の相互作用

    • Author(s)
      山本興子
    • Organizer
      第12回 日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.sudo.sd.keio.ac.jp

    • Related Report
      2012 Final Research Report
  • [Remarks] 慶應義塾大学 理工学部 須藤研究室 ホームページ

    • URL

      http://www.sudo.sd.keio.ac.jp/

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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