Development of statistical methods utilizing longitudinal data and time to event data effectively.
Project/Area Number |
22700297
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Statistical science
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Research Institution | Kurume University |
Principal Investigator |
YONEMOTO Koji 久留米大学, バイオ統計センター, 講師 (90398090)
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Project Period (FY) |
2010-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 同時モデリング / 非線形 / 縮小ランク回帰法 / 疫学 / 生存時間データ / 栄養疫学 / 経時データ / バイオマーカー / 栄養素 / 経時情報 / 観察研究 / モデル選択 |
Research Abstract |
For effect of risk factors on development of diseases, we proposed a modeling algorithm which can detect nonlinearity of the effect and confirmed performance of it by a simulation study. We showed that using joint modeling can reduce effect of regression dilution bias, i.e., joint modeling may be useful for observational studies. In nutrition epidemiology, variability of dietary patterns extracted by using reduced rank regression with biomarkers is large so generalizability of the pattern may be problematic. Moreover, we conducted many epidemiological studies, and many papers were published in international journals.
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Report
(5 results)
Research Products
(54 results)
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[Journal Article] Serum 1,25-dihydroxyvitamin D and the development of kidney dysfunction in a Japanese community: the Hisayama Study2014
Author(s)
Izumaru, K., Ninomiya, T., Nagata, M., Usui, T., Yoshida, D., Yonemoto, K., Fukuhara, M., Tsuruya, K., Kitazono, T.,; Kiyohara, Y
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Journal Title
Circulation Journal
Volume: 78
Pages: 732-737
DOI
Related Report
Peer Reviewed
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[Journal Article] Secular trends in cardiovascular disease and its risk factors in Japanese: half century data from the Hisayama Study, 1961-20092013
Author(s)
Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y
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Journal Title
Circulation
Volume: 128
Pages: 1198-1205
DOI
Related Report
Peer Reviewed
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[Journal Article] RECQL1 DNA Repair Helicase: A Potential Therapeutic Target and a Proliferative Marker against Ovarian Cancer2013
Author(s)
Sanada S, Futami K, Terada A, Yonemoto K, Ogasawara S, Akiba J, Yasumoto M, Sumi A, Ushijima K, Kamura T, Furuichi Y, Yano H
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Journal Title
Plos One
Volume: 8
Pages: 1-8
DOI
Related Report
Peer Reviewed
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[Journal Article] Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study2013
Author(s)
Sekita A, Arima H, Ninomiya T, Ohara T, Doi Y, Hirakawa Y, Fukuhara M, Hata J, Yonemoto K, Ga Y, Kitazono T, Kanba S, Kiyohara Y
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Journal Title
BMC Public Health
Volume: 13
Pages: -
DOI
Related Report
Peer Reviewed
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