Neural ultrastructure for inhibitory synaptic transmission between pyramidal cells

Research Project

Project/Area Number	22700373
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Nerve anatomy/Neuropathology
Research Institution	大学共同利用機関法人自然科学研究機構(岡崎共通研究施設) (2011) National Institutes of Natural Sciences Okazaki Research Facilities (2010)
Principal Investigator	TARUSAWA Etsuko 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 特別協力研究員 (00446262)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords	神経微細形態学
Research Abstract	It has reported that there is a inhibitory synaptic transmission between pyramidal cells without action potential of inhibitory neurons in visual cortex. To reveal the ultrastructure for the inhibitory synaptic transmission, we analyzed the localization of AMPA and kainate receptors, which are related molecules to the inhibitory synaptic transmission using SDS-FRL technique. These receptors were localized in the postsynaptic sites of pyramidal cells but not the inhibitory synaptic terminals.

Report

(3 results)