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Value coding of the striatal neurons

Research Project

Project/Area Number 22700424
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionNational Institute of Radiological Sciences

Principal Investigator

MINAMIMOTO Takafumi  独立行政法人放射線医学総合研究所, 分子イメージング研究センター, チームリーダー (50506813)

Research Collaborator HORI Yukiko  独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 博士研究員 (30433246)
BARRY J Richmond  米国国立衛生研究所(NIH), NIMH・Laboratory of Neuropsychology, 部門チーフ
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsシステム神経生理 / ニューロインフォマティクス / 動機付け / 報酬 / 意思決定 / 脳 / 動機づけ
Research Abstract

We studied how caudate neurons code temporal discounted values in an instrumental task. We recorded the 99 phasically active neurons in the caudate nucleus. Sixty-four neurons showed significant cue-related activity. 15 neurons(23%) showed significant linear relation with discounted outcome value(DV). Within 120 trials recording periods, more than 15% of motivational value was discounted as reward accumulation(i. e., devaluation). However, the DV related activity was not sensitive to this reward devaluation. These results suggest that a subset of single caudate neuron represent the discounted outcome value computed from the predicted reward size and delay duration. The caudate discounted value coding is insensitive to devaluation. These value coding appears to be involved in value based decision making rather than motivational regulation of action.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2011 2010 Other

All Presentation (4 results) Remarks (2 results)

  • [Presentation] 単一行動の実行を決める動機価値2011

    • Author(s)
      南本敬史
    • Organizer
      第30回日本基礎心理学会大会シンポジウム「選択・価値・戦略-強化をめぐる行動研究の展開と展望」
    • Place of Presentation
      慶応大学日吉キャンパス
    • Year and Date
      2011-12-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular imaging for motivational function and dysfunction2011

    • Author(s)
      南本敬史
    • Organizer
      第34回日本神経科学学会企画シンポジウム「分子イメージングと神経科学」
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 動機づけ行動において遅延割引による報酬価値を表現する尾状核神経活動2011

    • Author(s)
      堀由紀子、バリー・リッチモンド、南本敬史
    • Organizer
      2011年度包括脳ネットワーク夏のワークショップ
    • Place of Presentation
      神戸
    • Year and Date
      2011-08-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Neural coding of predicted and experienced outcome value with temporal discounting in the primate caudate nucleus.2010

    • Author(s)
      堀由紀子、バリー・リッチモンド、南本敬史
    • Organizer
      Neuro2010(第33回日本神経科学大会)
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Remarks] 所属研究室HPアドレス

    • URL

      http://www.nirs.go.jp/seika/brain/team/system_09.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.nirs.go.jp/seika/brain/team/system_09.html

    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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