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Development of a drug delivery system based on intelligent adaptive predictive control and a medical treatment strategy.

Research Project

Project/Area Number 22700466
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokushima

Principal Investigator

KASHIHARA Koji  徳島大学, 大学院・ソシオテクノサイエンス研究部, 准教授 (40463202)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywordsユーザ / インタフェース / 制御工学 / 生物 / 生体工学 / 認知科学 / 生物・生体工学 / ユーザインタフェース
Research Abstract

Shortage of anesthesiologists is a serious problem in local areas of Japan. Under such a condition, a computer-aided drug delivery system will beeffective for the judgment of a human operator . The support system based onintelligent adaptive predictive control can predict future responses to drug infusions, calculate optimal inputs, and represent those values on a monitor. Assessment studies revealed that the support system was able to assist human operators during the control of arterial blood pressure, regardless of sudden disturbance such as bleeding. The effective simulator to control the hemodynamics in heart failure was also constructed.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (38 results)

All 2013 2012 2011 2010 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (26 results) Remarks (4 results)

  • [Journal Article] Emotional attention modulates microsaccadic rate and direction2013

    • Author(s)
      Koji Kashihara
    • Journal Title

      Psychological Research

      Volume: 78 Issue: 2 Pages: 166

    • DOI

      10.1007/s00426-013-0490-z

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Automatic system to remove unpleasant images detected by pupil-size changes2012

    • Author(s)
      Koji Kashihara
    • Journal Title

      International Journal of Computer Science Issues

      Volume: Vol. 9, No. 1 Pages: 68-73

    • URL

      http://ijcsi.org/papers/IJCSI-9-1-1-68-73.pdf

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Automatic system to remove unpleasant images detected by pupil-size changes2012

    • Author(s)
      Koji Kashihara, et al
    • Journal Title

      International Journal of Computer Science Issues

      Volume: Vol.9(1) Pages: 68-73

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimal view angles in three-dimensional objects constructed from plane figures as mental images2011

    • Author(s)
      Koji Kashihara
    • Journal Title

      International Journal of Human-Computer Interaction

      Volume: Vol. 27, No. 7 Issue: 7 Pages: 606-619

    • DOI

      10.1080/10447318.2011.555301

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of task performance during mentally imagining three-dimensional shapes from plane figures2011

    • Author(s)
      Koji Kashihara
    • Journal Title

      Perceptual and Motor Skills

      Volume: Vol. 113, No. 1 Pages: 188-200

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of task performance during mentally imagining three-dimensional shapes from plane figures2011

    • Author(s)
      Koji Kashihara, et al
    • Journal Title

      Perceptual and Motor Skills

      Volume: Vol.113(1) Pages: 188-200

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of computer-aided drug delivery system with a human operator2010

    • Author(s)
      Koji Kashihara
    • Journal Title

      International Journal of Computer Science Issues

      Volume: Vol. 7, No. 5 Pages: 45-50

    • URL

      http://ijcsi.org/articles/Evaluation-of-Computer-aided-Drug-Delivery-System-with-a-Human-Operator.php

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of computer-aided drug delivery system with a human operator.2010

    • Author(s)
      Koji Kashihara, et al.
    • Journal Title

      International Journal of Computer Science Issues

      Volume: 7巻(5号) Pages: 45-50

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Fuzzy-PID 制御を用いた複数薬剤投与システムの検討2013

    • Author(s)
      柏原考爾
    • Organizer
      電子情報通信学会 MBE研究会
    • Place of Presentation
      徳島大学, 徳島市
    • Year and Date
      2013-07-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Classification of individually pleasant images based on neural networks with the bag of features2013

    • Author(s)
      Koji Kashihara
    • Organizer
      International Conference on Orange Technology (ICOT) 2013
    • Place of Presentation
      National Cheng Kung University, 台南・台湾
    • Related Report
      2012 Final Research Report
  • [Presentation] Fuzzy-PID制御を用いた複数薬剤投与システムの検討2013

    • Author(s)
      柏原 考爾
    • Organizer
      電子情報通信学会 信学技報
    • Place of Presentation
      徳島大学(徳島県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Classification of individually pleasant images based on neural networks with the bag of features.2013

    • Author(s)
      Koji Kashihara
    • Organizer
      Proceedings of International Conference on Orange Technology (ICOT) 2013
    • Place of Presentation
      Tainan(台湾)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 遺伝的アルゴリズムに基づいた遺跡発掘物の3 次元復元に関する研究2012

    • Author(s)
      柏原考爾
    • Organizer
      日本人間工学会中国・四国支部大会 講演論文集
    • Place of Presentation
      川崎医療福祉大学 , 倉敷市
    • Year and Date
      2012-12-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Three-dimensional reconstruction of artifacts based on a hybrid genetic algorithm2012

    • Author(s)
      Koji Kashihara
    • Organizer
      2012 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      Convention & Exhibition Center, ソウル・韓国
    • Year and Date
      2012-10-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Mentally framing a three-dimensional object from plane figures increases theta-band EEG activity2012

    • Author(s)
      Koji Kashihara
    • Organizer
      2012 International Conference on Affective Computing and Intelligent Interaction
    • Place of Presentation
      Holiday Inn East Taipei, 台北・台湾
    • Year and Date
      2012-02-27
    • Related Report
      2012 Final Research Report
  • [Presentation] Semantic categorization of emotional pictures2012

    • Author(s)
      Koji Kashihara
    • Organizer
      2012 International Conference on Affective Computing and Intelligent Interaction, Taipei
    • Place of Presentation
      Holiday Inn East Taipei, 台北・台湾
    • Year and Date
      2012-02-27
    • Related Report
      2012 Final Research Report
  • [Presentation] Semantic categorization of emotional pictures2012

    • Author(s)
      Koji Kashihara
    • Organizer
      2012 International Conference on Affective Computing and Intelligent Interaction, Lecture Notes in Information Technology, Vol.10, pp.229-234
    • Place of Presentation
      Holiday Inn East Taipei(台湾)
    • Year and Date
      2012-02-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Mentally framing a three-dimensional object from plane figures increases, theta-band EEG activity2012

    • Author(s)
      Koji Kashihara
    • Organizer
      2012 International Conference on Affective Computing and Intelligent Interaction, Lecture Notes in Information Technology, Vol.10, pp.224-228
    • Place of Presentation
      Holiday Inn East Taipei(台湾)
    • Year and Date
      2012-02-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Estimation of venous shapes acquired from CMOS camera images2012

    • Author(s)
      Koji Kashihara, et al.
    • Organizer
      Proceedings of the Eighteenth Korea-Japan Joint Workshop on Frontiers of Computer Vision (FCV2012)
    • Place of Presentation
      Kawasaki International Center, 川崎市
    • Year and Date
      2012-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] Estimation of venous shapes acquired from CMOS camera images2012

    • Author(s)
      Koji Kashihara
    • Organizer
      Proceedings of the Eighteenth Korea-Japan Joint Workshop on Frontiers of Computer Vision (FCV2012), pp.47-52
    • Place of Presentation
      Kawasaki International Center(神奈川県)
    • Year and Date
      2012-02-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 微小レベルの映像信号から静脈形状を高精度に推定するための解析手法の検討2011

    • Author(s)
      柏原考爾 他
    • Organizer
      電子情報通信学会 IE 研究会
    • Place of Presentation
      一の坊, 仙台市
    • Year and Date
      2011-10-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 微小レベルの映像信号から静脈形状を高精度に推定するための解析手法の検討2011

    • Author(s)
      柏原考爾
    • Organizer
      電子情報通信学会,信学技報,Vol.111,No.257,pp.49-54頁
    • Place of Presentation
      一の坊(宮城県)
    • Year and Date
      2011-10-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of automatic filtering system for individually unpleasant data detected by pupil-size change2011

    • Author(s)
      Koji Kashihara, et al.
    • Organizer
      Proceedings of 2011 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      Hilton Anchorage Hotel, アンカレッジ・アメリカ
    • Year and Date
      2011-10-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of automatic filtering system for individually unpleasant data detected by pupil-size change2011

    • Author(s)
      Koji Kashihara
    • Organizer
      Proceedings of 2011 IEEE International Conference on Systems, Man, and Cybernetics, pp.3311-3316
    • Place of Presentation
      Hilton Anchorage Conference Center(米国)
    • Year and Date
      2011-10-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] An analytical method for face detection based on image patterns of EEG signals in the time-frequency domain2011

    • Author(s)
      Koji Kashihara, et al.
    • Organizer
      Workshop on Brain-Machine Interfaces, 2011 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      Hilton Anchorage Hotel, アンカレッジ・アメリカ
    • Year and Date
      2011-10-10
    • Related Report
      2012 Final Research Report
  • [Presentation] An analytical method for face detection based on image patterns of EEG signals in the time-frequency domain2011

    • Author(s)
      Koji Kashihara
    • Organizer
      Workshop on Brain-Machine Interfaces, Proceedings of 2011 IEEE International Conference on Systems, Man, and Cybernetics, pp.25-29
    • Place of Presentation
      Hilton Anchorage Conference Center(米国)
    • Year and Date
      2011-10-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 時間-周波数領域における脳波信号の画像特徴量に基づいたBMI 解析手法の検討2011

    • Author(s)
      柏原考爾 他
    • Organizer
      第26回生体・生理工学シンポジウム
    • Place of Presentation
      立命館大学, 草津市
    • Year and Date
      2011-09-22
    • Related Report
      2012 Final Research Report
  • [Presentation] 瞳孔面積の変化に基づいた不快画像フィルタリングシステムの検討2011

    • Author(s)
      柏原考爾 他
    • Organizer
      第26回生体・生理工学シンポジウム
    • Place of Presentation
      立命館大学, 草津市
    • Year and Date
      2011-09-22
    • Related Report
      2012 Final Research Report
  • [Presentation] 瞳孔面積の変化に基づいた不快画像フィルタリングシステムの検討2011

    • Author(s)
      柏原考爾
    • Organizer
      第26回生体・生理工学シンポジウム論文集
    • Place of Presentation
      立命館大学(滋賀県)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 時間-周波数領域における脳波信号の画像特徴量に基づいたBMI解析手法の検討2011

    • Author(s)
      柏原考爾
    • Organizer
      第26回生体・生理工学シンポジウム論文集
    • Place of Presentation
      立命館大学(滋賀県)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effects of computer-aided drug delivery system with adaptive predictive control by human operators2010

    • Author(s)
      Koji Kashihara
    • Organizer
      2010 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      Harbiye Military Museum and Cultural Center, イスタンブール・トルコ
    • Year and Date
      2010-10-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of computer-aided drug delivery system with adaptive predictive control by human operators.2010

    • Author(s)
      Koji Kashihara
    • Organizer
      Proceedings of 2010 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      イスタンブール(トルコ)
    • Year and Date
      2010-10-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Three-dimensional reconstruction of artifacts based on a hybrid genetic algorithm.

    • Author(s)
      Koji Kashihara
    • Organizer
      Proceedings of 2012 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      Seoul(韓国)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 遺伝的アルゴリズムに基づいた遺跡発掘物の3次元復元に関する研究

    • Author(s)
      柏原 考爾
    • Organizer
      日本人間工学会中国・四国支部大会 講演論文集
    • Place of Presentation
      川崎医療福祉大学(岡山県)
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://pub2.db.tokushima-u.ac.jp/survey/person/214639/index.html

    • Related Report
      2012 Final Research Report
  • [Remarks] 研究成果一覧

    • URL

      http://pub2.db.tokushima-u.ac.jp/ERD/person/214639/work-ja.html

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://pub2.db.tokushima-u.ac.jp/ERD/person/214639/work-ja.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://pub2.db.tokushima-u.ac.jp/survey/person/214639/index.html

    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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