Research of the pathogenesis of chronic musculoskeletal pain-Behavioral and histological study of postnatal development factor-
Project/Area Number |
22700554
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Hamamatsu University |
Principal Investigator |
SAKURAI Hiroki 浜松大学, 保健医療学部・理学療法学科, 講師 (60454419)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | リハビリテーション医学 / 慢性痛 / 運動器 / モデル動物 |
Research Abstract |
We developed a musculoskeletal chronic pain model(LH model). In this model, the treatment to adult rats produced long-persisting pain behaviors, on the contrary, the treatment to young rats did not develop chronic pain behaviors. Histologically, damaged muscle tissues almost recovered in same time course with adult treated-rats and young treated-rats. These imply the possibility that some factors in pain pathway different from adult except for muscle recovery will be concerned in development of chronic pain.
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Report
(3 results)
Research Products
(4 results)