Development of a biopolymer delivery system using liquid crystalline fine capsules
Project/Area Number |
22760613
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Biofunction/Bioprocess
|
Research Institution | Tokyo City University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | ドラッグデリバリー / マイクロカプセル / 生体高分子 / マイクロ・ナノデバイス / マイクロバイオプロセス |
Research Abstract |
Efficient preparation method of “liquid crystalline fine capsules” for a carrier material in biopolymer delivery system was investigated. A mixture of liquid crystalline biomolecules such as phospholipids, cholesterol and long-chain fatty acids was used for a capsule-constituting material. Liquid crystalline fine capsules were successfully obtained with controlled diameters and high entrapment efficiencies (>80%) for water-soluble biopolymers using the novel combined methods of the microchannel emulsification and the solvent evaporation techniques.
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Report
(4 results)
Research Products
(45 results)