| Project/Area Number |
22780069
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | Kyushu University |
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Principal Investigator |
ZENDO Takeshi 九州大学, 農学研究院, 助教 (50380556)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 微生物機能 / 乳酸菌 / 抗菌ペプチド / バクテリオシン |
|---|
| Research Abstract |
Structures of antimicrobial peptides, bacteriocins, from lactic acid bacteria were analyzed, and some novel bacteriocins such as enterocin W, leucocyclicin Q and weissellicins YM were identified. Biosynthetic genes and their functions of some bacteriocins such as lacticin Q, enterocins NKR-5-3 and weissellicins YM were analyzed, and their biosynthetic regulation systems were partly unraveled. Action mechanisms of some bacteriocins were studied, and some factors for their specific antimicrobial actions were revealed.
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