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Generation of mice containing only paternal genome

Research Project

Project/Area Number 22780257
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Basic veterinary science/Basic zootechnical science
Research InstitutionHokkaido University

Principal Investigator

OTSUKA Saori  北海道大学, 獣医学研究科, 特任助教 (10566152)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords形態 / MRL/MpJマウス / 精巣内卵細胞 / 性分化 / 減数分裂 / 生殖腺 / 生殖細胞 / MRL/MpJ / Y染色体 / コンソミックマウス / QTL解析
Research Abstract

The testicular oocyte-producing pathway has at least 2 responsible genes, one on Chromosome Y and the other on autosome. The autosomal causative genes are suggested to be homozygous recessive. In addition, some XY primordial germ cells located in the vicinity of the rete testis or at the cranial edge of the fetal testis enter meiosis from E12. 5-14. 5 and differentiate as oocytes.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (5 results)

All 2011 2010 Other

All Presentation (2 results) Remarks (3 results)

  • [Presentation] MRL/MpJマウスにおける精巣内卵細胞への分化開始時期の特定2011

    • Author(s)
      大塚沙織
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪府立大学(大阪府・堺市)
    • Year and Date
      2011-09-20
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] MRLマウスの精巣内卵細胞出現に関与する遺伝的因子の解析2010

    • Author(s)
      大塚沙織
    • Organizer
      第150回日本獣医学会学術集会
    • Place of Presentation
      帯広畜産大学(北海道・帯広市)
    • Year and Date
      2010-09-18
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.vetmed.hokudai.ac.jp/organization/anat/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.vetmed.hokudai.ac.jp/organization/anat/index.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.vetmed.hokudai.ac.jp/organization/anat/index.html

    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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