| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2012: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2011: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2010: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Research Abstract |
There is no specific emotional task for patients with irritable bowel syndrome. Authors made the original task which provokes negative emotion in patients with irritable bowel syndrome. Irritable bowel syndrome-related pictures were presented to healthy controls and patients with irritable bowel syndrome. Healthy controls showed no changes in emotion, while patients with irritable bowel syndrome showed increase in negative emotion. Moreover, abdominal pain and urgency of defecation were exaggerated. This task is applicable for functional magnetic resonance imaging. In Voxel-based morphometry analysis, patients with irritable bowel syndrome showed significant increase of signal at premotor area and supplementary motor area. And in Diffusion tensor Imaging analysis, the area(38, -46, -2) represented significant increase of signal in patients with irritable bowel syndrome.
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