Research Project
Grant-in-Aid for Young Scientists (B)
In the damaged rat liver, soluble catechol-0-methyltransferase(COMT) increased as a phosphorylated form and decreased as a dephosphorylated form. This finding raised the possibility that the COMT protein is associated with liver function. To evaluate the association between COMT genotypes and liver function, we used data from the Japan Multi-Institutional Collaborative Cohort(J-MICC) Study. In this study, we revealed that a COMT polymorphism(rs4680 : Val158Met(G/ A)) affected liver function.
All 2012 2011 2010
All Journal Article (11 results) (of which Peer Reviewed: 11 results) Presentation (7 results)
The Journal of Allergy and Clinical Immunology
Volume: (in press) Issue: 1 Pages: 113-121.e2
10.1016/j.jaci.2012.02.023
Maturitas
Volume: 71(4) Issue: 4 Pages: 369-375
10.1016/j.maturitas.2011.12.021
Gene
Volume: 496 Issue: 2 Pages: 97-102
10.1016/j.gene.2012.01.015
International Archives of Occupational and Environmental Health
Volume: 84(8) Issue: 8 Pages: 927-935
10.1007/s00420-011-0618-7
Analytica chimica acta
Volume: 706(2) Issue: 2 Pages: 321-327
10.1016/j.aca.2011.08.034
Biochemical and Biophysical Research Communications
Volume: 410 Issue: 1 Pages: 29-33
10.1016/j.bbrc.2011.05.099
Journal of Epidemiology
Volume: 21 Issue: 3 Pages: 223-235
10.2188/jea.JE20100139
10030212853
Chemosphere
Volume: 82(5) Issue: 5 Pages: 656-662
10.1016/j.chemosphere.2010.11.008
Volume: 82 Pages: 656-662
Volume: 79(7) Issue: 7 Pages: 706-712
10.1016/j.chemosphere.2010.02.050
Volume: 79 Pages: 706-712