• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of the diagnostic procedure of the pervasive developmental disorder using the near-infrared spectroscopy

Research Project

Project/Area Number 22791109
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionThe University of Tokyo

Principal Investigator

KUWABARA Hitoshi  東京大学, 医学部附属病院, 助教 (50456117)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords精神生理学 / 広汎性発達障害 / 神経生理学
Research Abstract

We compared 42 healthy control group and schizophrenia group which matched age, with 42 patients with PDD using the 52 channels NIRS instrument(ETG4000). We used a word fluency task for a cognitive activation, and analyzed mean change of the oxy-hemoglobin concentration during the task. About each measurement of 52 channels, we conducted the one-way analysis of variance between three groups. Activation was significantly smaller in PDD group and schizophrenia group than the healthy control group in Ch1 and Ch29. Activation was significantly larger than schizophrenia group in the healthy control group and PDD group in Ch14, Ch25, Ch36, and Ch46. Activation was significantly smaller in schizophrenia group than the healthy control group in Ch28.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (5 results)

All 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (2 results)

  • [Journal Article] Developmental changes of prefrontalactivation in humans a near-infraredspectroscopy study of preschool childrenand adults2011

    • Author(s)
      Kawakubo Y, Kono T, Takizawa R, KuwabaraH, Ishii-Takahashi A, Kasai K
    • Journal Title

      PLoS One

      Volume: 6

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Developmental changes of prefrontal activation in humans : a near-infrared spectroscopy study of preschool children and advilts2011

    • Author(s)
      Kawakubo Y, Kono T, Takizawa R, Kuwabara H, Ishii-Takahashi A, Kasai K
    • Journal Title

      PLoS One

      Volume: 6

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Factors affecting clinicians' decision as to whether to prescribe psychotropic medication or not in treatment of tic disorders2011

    • Author(s)
      Hitoshi.Kuwabara, Takafumi Shimada, Toshiaki Kono, Yukiko Kano
    • Journal Title

      Brain and Development

      Volume: (in print)(掲載確定)

    • NAID

      10031049452

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 自閉症スペクトラム障害家系の全エクソン解析2011

    • Author(s)
      桑原斉
    • Organizer
      第52回日本児童青年期精神医学会
    • Place of Presentation
      徳島県徳島市
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Exome sequencing of a multiplex family with Asperger' s disorder2010

    • Author(s)
      Hitoshi Kuwabara, Takafumi Shimada, Miki Bundo, Chihiro Kakiuchi, Kazuya Iwamoto, Mamoru Tochigi, Tsukasa Sasaki, Yukiko Kano, Kiyoto Kasai
    • Organizer
      World congress on psychiatric genetics
    • Place of Presentation
      Athens, Greek
    • Year and Date
      2010-10-05
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi