Role of brain derived neurotrophic factor 3 in perirhinal neurons during visual object discrimination learning

• Project/Area Number: 22791151
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Psychiatric science
• Research Institution: University of Miyazaki
• Principal Investigator: ABE Hiroshi 宮崎大学, 医学部, 講師 (20344848)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 嗅周皮質 / 神経栄養因子 / 物体弁別

Research Abstract

It is known that the perirhinal cortex in the brain plays some important roles on the memory for objects. This study suggested that neurotrophin receptor(TrkB) would play some important roles on retention of the memory for objects in rats. However, injection of the neurotrophic factor 3 into the perirhinal cortex did not affect the memory for objects.

Research Products

• [Journal Article] Effect of aripiprazole on methamphetamine-induced disruption of latent inhibition in rats (2011)
  • Author(s): Hisae Matsuo, Hiroshi Abe, Tetsuya Ikeda, Kosuke Ebihara, Ryuichiro Takeda, Toshikazu Nishimori, Yasushi Ishida
  • Journal Title: Journal of Behavioral and Brain Science Volume: 1-3 Pages: 167-171
  • Peer Reviewed
• [Journal Article] Differential expression of FosB, c-Fos, and Zif268 in forebrain regions after acute or chronic l-DOPA treatment in a rat model of Parkinson disease (2011)
  • Author(s): Kosuke Ebihara, Yasushi Ishida, Ryuichiro Takeda, Hiroshi Abe, Hisae Matsuo, Keiichi Kawai, Yasuhiro Magata, Toshikazu Nishimori
  • Journal Title: Neuroscience Letters Volume: 496 Pages: 90-94
  • Peer Reviewed
• [Journal Article] Differential expression of FosB, c-Fos, and Zif268 in forebrain regions after acute or chronic L-DOPA treatment in a rat model of Parkinson's disease (2011)
  • Author(s): Ebihara K, et al
  • Journal Title: Neurosci Lett Volume: 496 Issue: 2 Pages: 90-94
  • DOI: 10.1016/j.neulet.2011.03.087
  • Peer Reviewed
• [Presentation] Functional dissociation between the perirhinal cortex and hippocampus for reference memoryperformance on object and place discrimination tasks in rats (2010)
  • Author(s): Hiroshi Abe, Yasushi Ishida, Nodoka Okada, Tsuneo Iwasaki
  • Organizer: 40th Annual Meeting, Society For Neuroscience
  • Place of Presentation: San Diego
• [Presentation] Functional dissociation between the perirhinal cortex and hippocampus for reference memory performance on object and place discrimination tasks in rats (2010)
  • Author(s): Abe, et al.
  • Organizer: 40th Annual Meeting, Society For Neuroscience
  • Place of Presentation: San Diego, U.S.A.