New labeling method with F-18 and synthesis of[F-18] fluoro amino acid

• Project/Area Number: 22791214
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: Yokohama City University
• Principal Investigator: ARISAWA Tetsu 横浜市立大学, 医学研究科, 特任助教 (30508338)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: PET / 有機化学 / F-18 / 放射性同位元素 / フッ素ガス / ^<18>F

Research Abstract

In recent days, positron emission tomography(PET) has been developed in clinical diagnosis or preclinical studies. However, synthesis of PET tracer is not applicable to normal chemical synthetic strategy. This project aimed to development of novel F-18 labeling method and synthesis of[F-18] fluoro amino acid as PET tracer.