Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Research Abstract |
We performed microarray analyses for chemoresistant cell lines such as gastric cancer and esophageal cancer. We found chemoresistance related genes for 5-FU, oxaliplatin, and CPT-11, respectively. Especially, in oxaliplatin reistant cell lines, we discovered common up regulated genes such as AGR2, MUC4, LGALS7, GJB6, and KDM5D, and down regulated genes such as FLRT2, SLC25A27, ANKRD20A1, FRG1, and SAMD4A.
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