| Project/Area Number |
22791296
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Wakayama Medical University |
|---|
Principal Investigator |
IIDA Takeshi 和歌山県立医科大学, 医学部, 学内助教 (30453187)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | Th17 / Treg / 腫瘍 / IL-17 / Foxp3 |
|---|
| Research Abstract |
In the examination of the tumor growth curve in the mouse in vivo subcutaneous tumor model, in the mIL-17A-shRNA group, it significantly showed tumor growth depression effect as compared with the PBS group of the control SNC group.
It was suggested that IL-17 acted as a tumor growth factor in the tumor microenvironment.
|
