Establishment of a novel biomarker of testicular cancer
| Project/Area Number |
22791463
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 精巣腫瘍 / セミノーマ / バイオマーカー / DNMT3A遺伝子 |
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| Research Abstract |
We conducted flow cytometry analysis about DNMT3A antibody of mouse and rabbit. There was no reaction with Hs1 cell arriving from normal testicular tissues. However, there was a significant reaction with NCCIT cell arriving from testicular cancer tissues, and this reaction was amplified by Triton preparation. We also conducted immunohistochemical analysis of DNMT3A for human testicular seminoma tissues, and confirmed that human seminoma cells were positively stained.
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Report
(3 results)
Research Products
(29 results)
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[Journal Article] Predicting the severity of acute urinary toxicity after brachytherapy with iodine-125 for localized prostate cancer2011
Author(s)
Takeda K, Jingu K, Koto M, Fujimoto K, Narazaki K, Kubozono M, Saito H, Yamada S, Mitsuduka K, Ishidoya S, Ariga H, Arai Y, Yamada S
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Journal Title
The Tohoku journal of experimental medicine
Volume: 223巻
Pages: 55-60
NAID
Related Report
Peer Reviewed
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[Journal Article] Core 2 N-acetylglucosaminyltransferase-1 expression induces aggressive potential of testicular germ cell tumor.2010
Author(s)
Hatakeyama S, Kyan A, Yamamoto H, Okamoto A, Sugiyama N, Suzuki Y, Yoneyama T, Hashimoto Y, Koie T, Yamada S, Saito H, Arai Y, Fukuda M, Ohyama C
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Journal Title
Int J Cancer
Volume: 127巻
Pages: 1052-1059
Related Report
Peer Reviewed
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[Presentation] 前立腺癌に対する根治的前立腺摘除術後の排尿症状改善と前立腺サイズとの関連性2011
Author(s)
宮里実, 大原慎也, 三塚浩二, 山田成幸, 齋藤英郎, 海法康裕, 伊藤明宏, 中川晴夫, 石戸谷滋人, 斎藤誠一, 荒井陽一
Organizer
第49回日本癌治療学会学術総会
Place of Presentation
名古屋
Year and Date
2011-10-27
Related Report
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