Functional analysis of Talin1 in prostate cancer and application into taylormade medicine
| Project/Area Number |
22791469
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Chiba University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 前立腺癌 / マーカー / 免疫染色 / テーラーメード医療 / 免疫染 / 診断 |
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| Research Abstract |
Expression of Talin1was significantly up-regulated in prostate cancer compare to benign lesion. Talin1 expression partially correlated with Gleason Score and up-regulated in invasive prostate cancer(pT3) compare to organ confined prostate cancer(pT2). Concerning pre-treatment nomogram, high Talin1 expression may predict invasive prostate cancer among pre-treatment cT1c cases.
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Report
(3 results)
Research Products
(16 results)
