Clarification of oxygen sensor system of the mouse trachea epithelia
| Project/Area Number |
22791598
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Osaka University |
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Principal Investigator |
ISHIDA Yusuke 大阪大学, 医学系研究科, 講師 (30381809)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 酸素センサー / 低酸素 / 味蕾様構造物 / 気管上皮 / in situ hybridization / 脳・神経 / 神経科学 / 免疫組織化学 |
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| Research Abstract |
Oxygen is essential for life, however, oxygen sensor and the transmission system are still unknown. We hypothesized that oxygen is sensed on trachea epithelia and began to research on oxygen-sensing system of the mouse trachea epithelia. Our results indicated that taste bud-like structure in the trachea epithelia is oxygen sensor. Furthermore, it was indicated that ATP and ATP receptor play crucial roles on oxygen-sensing systems of the mouse trachea epithelia.
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Report
(3 results)
Research Products
(4 results)
