Association of tenascin-W expression with mineralization in mouse calvarial development

Research Project

Project/Area Number	22791741
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Plastic surgery
Research Institution	Osaka Medical College
Principal Investigator	MIKURA Ayako 大阪医科大学, 医学部, 非常勤医師 (50533957)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000) Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords	頭蓋冠 / 発生 / 早期骨癒合症 / 頭蓋冠早期癒合症 / 縫合閉鎖 / テネイシン / 頭蓋冠早期骨癒合症
Research Abstract	We carried tenascin W in the mouse calvarium suture and I examined it whether a suture did concrescence(closedown) and examined a change of the onset of gene, but a big change was not seen in bone union by supply of tenascin W in in vivo experiment system using the mouse. However, the tendency that the closedown of the suture delayed when I was sustained release and triggered fibroblast growth factor(FGF) 2 at the closedown time of the suture in the process was recognized.

Report

(3 results)