Identification and characterization of the surface proteins in periodontal pathogens
| Project/Area Number |
22791772
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
OOGAI Yuichi 鹿児島大学, 医歯学総合研究科, 助教 (40511259)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 歯周病原因菌 / 外膜タンパク / 補体抵抗性 / 細菌学 |
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| Research Abstract |
Our research has been focused on identification and virulence of surface protein in periodontal pathogens. We did not find the novel virulence factor in surface proteins of Fusobacteriu nucleatum. The cells of F. nucleatum are fusiform rods. We found that this morphology formation was involved in two autotransporter proteins found in outer membrane proteins of F. nucleatum. We also found that complement resistance of Tannerella forsythia was involved in S-layer composed from two high molecular weight proteins.
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Report
(3 results)
Research Products
(2 results)
