Modulation of salivary secretion by novel transport regulation factor

Research Project

Project/Area Number	22791789
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Functional basic dentistry
Research Institution	Hiroshima University
Principal Investigator	KITAYAMA Tomoya 広島大学, 大学院・医歯薬学総合研究科, 助教 (60363082)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	PRIP / 分泌 / インスリン / GABARAP / 開口分泌
Research Abstract	PRIP(a novel transport regulation factor) was knocked down by siRNA in MIN6 cells(murineβcell line). We found that the down-regulation of PRIP induces a reduction of insulin secretion, the process of which is modulated by GABARAP, a PRIP binding protein.

Report

(3 results)