Examination of the ASK1 involvement in a reactive oxygen spiecies-inducitive osteoclast activation signal.
| Project/Area Number |
22791805
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional basic dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | シグナル伝達 / ストレス / 破骨細胞 / 骨芽細胞 |
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| Research Abstract |
It has been reported that reactive oxygen species is important for osteoclastogenesis and activation of apoptosis signal regulating kinase 1(ASK1). However, the role of ASK1 on osteoclastogenesis is still unknown. We investigated wheather ASK1 is involved in osteoclastogenesis and found that ASK1 involved in reactive oxygen spiecies-inducitive osteoclast activation.
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Report
(3 results)
Research Products
(16 results)
