The role of autophagy in a tooth development
| Project/Area Number |
22792052
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | オートファジー / 発生 / 歯 / 骨組織 / 矯正歯科 / 顎骨 |
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| Research Abstract |
This study is to be clear the role of autophagy in the process of hard tissue development, especially tooth. At first, we found the difference between tooth development of wild type mouse and that of ATG5 KO(autophagy blocked) mice.
In other hand, we also noticed that the influence of autophagy is larger in bone tissue development rather than tooth development in my experiment process. These results were presented on academic journals and meetings.
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Report
(3 results)
Research Products
(14 results)
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[Journal Article] Sox9 expression during fracture repair2011
Author(s)
Shintaku Y., Murakami T., Yanagita T., Kawanabe N., Fukunaga T., Matsuzaki K., Uematsu S., Yoshida Y., Kamioka H., Takano-Yamamoto T., Takada K., Yamashiro T
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Journal Title
Cells Tissues Organs
Volume: 194
Issue: 1
Pages: 38-48
DOI
Related Report
Peer Reviewed
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[Journal Article] Core binding factor beta functions in the maintenance of stem cells and orchestrates continuous proliferation and differentiation in mouse incisors2011
Author(s)
Kurosaka H, Islam MN, Kuremoto K, Hayano S, Nakamura M, Kawanabe N, Yanagita T, Rice DP, Harada H, Taniuchi I, Yamashiro T
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Journal Title
Stem Cells
Volume: 29巻
Issue: 11
Pages: 1792-1803
DOI
Related Report
Peer Reviewed
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