Research of respiratory response induced by raphe obscurus neurons to hypoxic condition through activating medullary respiratory center.
| Project/Area Number |
22890109
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
HARADA Takeshi 大阪大学, 歯学部附属病院, 医員 (00403030)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥2,977,000 (Direct Cost: ¥2,290,000、Indirect Cost: ¥687,000)
Fiscal Year 2011: ¥1,417,000 (Direct Cost: ¥1,090,000、Indirect Cost: ¥327,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 低酸素センサー / 呼吸活動 / 縫線核 / セロトナージックニューロン / パッチクランプ |
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| Research Abstract |
Raphe nucleus neuron, which is projecting to the respiratory center in the cerebrum, responded to hypoxic stimulation differently between outside sub-nuclei and median sub-nuclei. These changes of the depolarization had not received input from other neuron. These were due to characteristics of membrane of Raphe nucleus neuron. Serotonin from Raphe nucleus neuron terminal controlled number of pacemaker in the respiratory center.
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Report
(3 results)
Research Products
(6 results)
