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Research of respiratory response induced by raphe obscurus neurons to hypoxic condition through activating medullary respiratory center.

Research Project

Project/Area Number 22890109
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionOsaka University

Principal Investigator

HARADA Takeshi  大阪大学, 歯学部附属病院, 医員 (00403030)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥2,977,000 (Direct Cost: ¥2,290,000、Indirect Cost: ¥687,000)
Fiscal Year 2011: ¥1,417,000 (Direct Cost: ¥1,090,000、Indirect Cost: ¥327,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords低酸素センサー / 呼吸活動 / 縫線核 / セロトナージックニューロン / パッチクランプ
Research Abstract

Raphe nucleus neuron, which is projecting to the respiratory center in the cerebrum, responded to hypoxic stimulation differently between outside sub-nuclei and median sub-nuclei. These changes of the depolarization had not received input from other neuron. These were due to characteristics of membrane of Raphe nucleus neuron. Serotonin from Raphe nucleus neuron terminal controlled number of pacemaker in the respiratory center.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2011 2010

All Presentation (6 results)

  • [Presentation] 口唇裂・口蓋裂に伴う上顎骨劣成長に対する上顎骨前方部骨延長術(MASDO)の検討2011

    • Author(s)
      原田丈司、相川友直、石濱孝二、樋口将隆、牛村彩子、田中晋、石橋美樹、永谷俊介、奥野恵実、山本奈穂、木田久美子、田中輝、程壮樹、飯田征二、古郷幹彦
    • Organizer
      第21回日本顎変形症学会総会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2011-06-17
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 口腔癌N0頸部の治療方針に関する決定樹解析と治療閾値2011

    • Author(s)
      田中徳昭、沢井奈津子、原田丈司、大倉正也、古郷幹彦
    • Organizer
      第35回日本頭頸部癌学会
    • Place of Presentation
      ウインクあいち(愛知)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔癌N0頸部の治療方針に関する決定樹解析と治療閾値2011

    • Author(s)
      田中徳昭、沢井奈津子、原田丈司、大倉正也、古郷幹彦
    • Organizer
      第35回日本頭頸部癌学会
    • Place of Presentation
      ウインクあいち(東京)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 不確縫線核ニューロンによる呼吸恒常性の維持機構2010

    • Author(s)
      山西整、原田丈司、石濱孝二、森本泰成、宮成典、辻忠孝、大槻浩一、古郷幹彦
    • Organizer
      第55回日本口腔外科学会総会
    • Place of Presentation
      千葉幕張メッセ(千葉)
    • Year and Date
      2010-10-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 頸部廓清術における副神経麻痺の評価2010

    • Author(s)
      原田丈司、山田謙一、沢井奈津子、住岡聡、山西整、大倉正也、古郷幹彦
    • Organizer
      第55回日本口腔外科学会総会
    • Place of Presentation
      千葉幕張メッセ(千葉)
    • Year and Date
      2010-10-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 不確縫線核ニューロンによる呼吸恒常性の維持機構2010

    • Author(s)
      山西整, 他
    • Organizer
      第55回(社)日本口腔外科学会総会・学術大会
    • Place of Presentation
      千葉 幕張メッセ
    • Year and Date
      2010-10-17
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-27   Modified: 2016-04-21  

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