| Project/Area Number |
23310026
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental impact assessment/Environmental policy
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| Research Institution | Toyo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TATSUTA Haruki 琉球大学, 農学部, 准教授 (50370268)
NAGASAKA Seiji 東洋大学, 生命科学部, 教授 (60534013)
HIROTSU Naoki 東洋大学, 生命科学部, 准教授 (40584389)
SAKAMOTO Masaki 富山県立大学, 工学部, 講師 (20580070)
SHIMIZU Kazuya 東洋大学, 生命科学部, 講師 (10581613)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKEI Hiroyuki 東洋大学, 生命科学部, 教授 (40520789)
KATSUMATA Masakazu 浜松ホトニクス株式会社, 中央研究所, 部員 (80394005)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
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| Keywords | ナノマテリアル / 生態系影響評価 / 生態毒性 / 銀ナノ粒子 / 個体群理論 / 生態リスク評価 / 活性汚泥 / 水生植物 / 藻類 / 動物プランクトン / メダカ / 銀ナノコロイド / 毒性 |
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| Research Abstract |
Minimum bactericidal concentration of silver nanocolloids (SNCs) to active sludge was 5 mg/L. Toxicities of SNCs to cyanobacteria and micro algae were comparatively high, in addition, nano-size dependent toxicity was observed. In case of SNCs exposure to aquatic plants, there was inhibition of roots growth because released Ag+ inhibited glutathione reductase and following increase of H2O2 in roots reduced catalase activity. There is no significant difference between SNCs and AgNO3 in acute mobility inhibition test of invertebrates. Main toxic factor in reproduction test of invertebrates was Ag+. In fish, it was observed that shortened body length, reduction of heart beating, ischemia and kyphosis were induced by SNCs exposure. SOD, CAT and GSH were significantly reduced, and apoptosis inhibition was observed. Moreover, intrinsic growth rate of fish was significantly decreased by SNCs exposure.
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