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Development of carbon nanotube-ceramics composites as high performance biomaterials

Research Project

Project/Area Number 23360303
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Inorganic materials/Physical properties
Research InstitutionShinshu University

Principal Investigator

TARUTA Seiichi  信州大学, 学術研究院工学系, 教授 (00217209)

Co-Investigator(Kenkyū-buntansha) SAITO Naoto  信州大学, 学術研究院保健学系, 教授 (80283258)
Project Period (FY) 2011-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Keywordsバイオマテリアル / カーボンナノチューブ / アルミナ / 複合体 / 微構造制御 / 骨伝導性 / 機械的性質 / 発泡体 / 生体材料
Outline of Final Research Achievements

In order to develop the long-operating life artificial joints, carbon nanotubes (CNTs) were combined with alumina ceramics as reinforcement. We found that to enhance the fracture toughness of the composites, it was necessary not only that thinner CNTs having a few defects were dispersed uniformly in the composites but also that the microstructures of the composites were finer. Also, it is known that alumina ceramics are originally bioinert materials. So we found that alumina ceramics, which were ground coarsely and then heated with conc. phosphoric acid, had possibility to show bioactivity. The bioactivity is required property to use the alumina ceramics as artificial bone. Furthermore, in order to apply CNTs as scaffolds to regenerate living bone, CNTs/glass foam composites were fabricated. The foam composites in which CNTs were dispersed relatively uniform in the walls of pores were obtained.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (38 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 1 results) Presentation (28 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Fabrication and Fracture Toughness of CNTs/alumina Composites with Fine Microstructures2014

    • Author(s)
      Naoki Ueda, Tomohiko Yamakami, Tomohiro Yamaguchi, Morinobu Endo, Naoto Saito, Seiichi Taruta
    • Journal Title

      Key Engineering Materials

      Volume: 617 Pages: 205-208

    • DOI

      10.4028/www.scientific.net/kem.617.205

    • NAID

      120007101159

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surface modification of carbon nanofibers with SiC by heating different SiO vapor sources in argon atmosphere2014

    • Author(s)
      Guosheng Xu, Tomohiko Yamakami, Tomohiro Yamaguchi, Morinobu Endo, Seiichi Taruta, Isao Kubo
    • Journal Title

      Journal of the Ceramic Society of Japan

      Volume: 122 Issue: 1429 Pages: 822-828

    • DOI

      10.2109/jcersj2.122.822

    • NAID

      130004951028

    • ISSN
      1348-6535, 1882-0743
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pressureless sintering of carbon nanofiber/SiC composites and their properties2014

    • Author(s)
      Guosheng Xu, Tomohiko Yamakami, Tomohiro Yamaguchi, Morinobu Endo, Seiichi Taruta, Isao Kubo
    • Journal Title

      International Journal of Applied Ceramic Technology

      Volume: 11 Issue: 2 Pages: 280-288

    • DOI

      10.1111/ijac.12131

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of CNF content on microstructure and fracture toughness of CNF/alumina composites2014

    • Author(s)
      Naoki Ueda, Tomohiko Yamakami, Tomohiro Yamaguchi, Yuki Usui, Kaoru Aoki, Morinobu Endo, Naoto Saito, Seiichi Taruta
    • Journal Title

      Journal of the Ceramic Society of Japan

      Volume: 122 Issue: 1424 Pages: 292-299

    • DOI

      10.2109/jcersj2.122.292

    • NAID

      130003393109

    • ISSN
      1348-6535, 1882-0743
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microstructure development and fracture toughness of acid-treated carbon nanofibers/alumina composites2012

    • Author(s)
      Naoki Ueda, Tomohiko Yamakami, Tomohiro Yamaguchi, Kunio Kitajima, Yuki Usui, Kaoru Aoki, Morinobu Endo, Naoto Saito, Seiichi Taruta
    • Journal Title

      Journal of the Ceramic Society of Japan

      Volume: 120 Pages: 560-568

    • NAID

      130004950756

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deposition of apatite on carbon nanofibers in simulated body fluid2011

    • Author(s)
      Taruta S, Kidokoro K, Yamakami T, Yamaguchi T, Kitajima K, Endo M, Saito N
    • Journal Title

      Journal of Nanomaterials

      Volume: 2011 Pages: 1-8

    • DOI

      10.1155/2011/935320

    • NAID

      120007113685

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of CNT toxicity in comparison to tattoo ink nanoparticles for use as a biomaterial2011

    • Author(s)
      Hara K, et al
    • Journal Title

      Mater Today

      Volume: VOL.14 Pages: 434-440

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Application of carbon fibers to biomaterials : new era of nano-level control of carbon fibers after 30-years of development2011

    • Author(s)
      Saito N, et al
    • Journal Title

      Chem Soc Rev

      Volume: VOL.40 Pages: 3824-3834

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] アルミナ原料としてγ-アルミナを用いて作製したCNFs/アルミナ複合体の微構造変化2015

    • Author(s)
      西尾翔多・山口朋浩・齋藤直人・樽田誠一
    • Organizer
      日本セラミックス協会2015年年会
    • Place of Presentation
      岡山大学津島キャンパス
    • Year and Date
      2015-03-18 – 2015-03-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] アルミナコーティングしたカーボンナノチューブ複合アルミナセラミックスの作製と機械的性質2014

    • Author(s)
      鈴木彩香,荒井善生,植田直樹,山上朋彦,山口朋浩,樽田誠一
    • Organizer
      日本セラミックス協会第27回秋季シンポジウム
    • Place of Presentation
      鹿児島大学郡元キャンパス
    • Year and Date
      2014-09-09 – 2014-09-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 研磨およびリン酸処理したアルミナセラミックスの擬似体液中での挙動2014

    • Author(s)
      福井亮太,山上朋彦,植田直樹,山口朋浩,齋藤直人,樽田誠一
    • Organizer
      第30回日本セラミックス協会関東支部研究発表会
    • Place of Presentation
      栃木県那須青年の家
    • Year and Date
      2014-09-02 – 2014-09-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] 酸処理したCNTsを複合化したアルミナセラミックスの微構造変化2014

    • Author(s)
      名和大智,山上朋彦,植田直樹,山口朋浩,齋藤直人,樽田誠一
    • Organizer
      第30回日本セラミックス協会関東支部研究発表会
    • Place of Presentation
      栃木県那須青年の家
    • Year and Date
      2014-09-02 – 2014-09-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Deposition of apatite on alumina ceramics treated in phosphoric acid solution and calcium chloride solution2014

    • Author(s)
      Seiichi Taruta, Ryota Fukui, Naoki Ueda, Tomohiko Yamakami, Tomohiro Yamaguchi, Naoto Saito
    • Organizer
      5th International Congress on Ceramics
    • Place of Presentation
      Beijing International Convention Center (China)
    • Year and Date
      2014-08-17 – 2014-08-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] Pressureless sintering of SiC-coated carbon nanofiber/SiC composites and their properties2014

    • Author(s)
      Guosheng Xu, Tomohiko Yamakami, Tomohiro Yamaguchi, Morinobu Endo, Seiichi Taruta, Isao Kubo
    • Organizer
      5th International Congress on Ceramics
    • Place of Presentation
      Beijing International Convention Center (China)
    • Year and Date
      2014-08-17 – 2014-08-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] CNTs/アルミナ複合体の微構造と破壊靭性に与えるCNTs繊維径の影響2014

    • Author(s)
      植田直樹,,山上朋彦,山口朋浩,遠藤守信,齋藤直人,樽田誠一
    • Organizer
      日本セラミックス協会2,014年年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス (横浜市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ベーマイトが析出したカーボンナノチューブの加熱変化2014

    • Author(s)
      鈴木彩香,荒井善生,植田直樹,山上朋彦,山口朋浩,樽田誠一
    • Organizer
      日本セラミックス協会2,014年年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス (横浜市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] CNFs/アルミナ複合体の電気伝導度に与えるCNFs分布状態の影響2013

    • Author(s)
      植田直樹,,山上朋彦,山口朋浩,遠藤守信,齋藤直人,樽田誠一
    • Organizer
      日本セラミックス協会第26回シンポジウム
    • Place of Presentation
      信州大学長野キャンパス (長野市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 生体活性アルミナセラミックスの作製2013

    • Author(s)
      福井亮太,植田直樹,山口朋浩,齋藤直人,樽田誠一
    • Organizer
      日本セラミックス協会第26回シンポジウム
    • Place of Presentation
      信州大学長野キャンパス (長野市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] SiCをコーディングしたカーボンナノファイバー複合SiCの常圧焼結と機械的性質2013

    • Author(s)
      徐 国勝,山口朋浩,遠藤守信,樽田誠一,久保 勲
    • Organizer
      日本セラミックス協会第26回シンポジウム
    • Place of Presentation
      信州大学長野キャンパス (長野市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] カーボンナノファイバー複合ガラス発泡体の作製2013

    • Author(s)
      杉山貴大,山口朋浩,樽田誠一
    • Organizer
      第29回日本セラミックス協会関東支部研究発表会
    • Place of Presentation
      埼玉大学 (さいたま市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fabrication and fracture toughness of CNTs/alumina composites with fine microstructures2013

    • Author(s)
      Naoki Ueda, Tomohiko Yamakami, Tomohiro Yamaguchi, Morinobu Endo, Naoto Saito, Seiichi Taruta
    • Organizer
      Second International Symposium on Inorganic and Enviromental materials
    • Place of Presentation
      University of Rennes 1 (Rennes, France)
    • Related Report
      2013 Annual Research Report
  • [Presentation] カーボンナノファイバー/アルミナ複合体の微構造および破壊靭性に与えるカーボンナノファイバー添加量の影響2013

    • Author(s)
      植田直樹,山上朋彦,山口朋浩,遠藤守信,齋藤直人,樽田誠一
    • Organizer
      日本セラミックス協会2013年年会
    • Place of Presentation
      東京工業大学(東京)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 繊維径の異なるCNTを複合化したアルミナセラミックスの微構造変化および機械的性質2012

    • Author(s)
      植田直樹, 他
    • Organizer
      日本セラミックス協会2012年年会
    • Place of Presentation
      京都大学(京都市)
    • Year and Date
      2012-03-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] カーボンナノファイバー複合SiCの常圧焼結と機械的性質2012

    • Author(s)
      徐国勝, 他
    • Organizer
      日本セラミックス協会2012年年会
    • Place of Presentation
      京都大学(京都市)
    • Year and Date
      2012-03-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] Grain growth behavior of acid-treated CNTs/alumina composites2012

    • Author(s)
      Ueda N, et al
    • Organizer
      The 50th Anniversary Symposium on Bacis Science of Ceramics
    • Place of Presentation
      国際ファッションセンター(東京都)
    • Year and Date
      2012-01-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] 金属アルコキシドを用いたカーボンナノファイバーへのアルミナコーティング2012

    • Author(s)
      荒井善生, 他
    • Organizer
      セラミックス基礎科学討論会 第50回記念大会
    • Place of Presentation
      国際ファッションセンター(東京都)
    • Year and Date
      2012-01-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Estimation of microstructure development of CNTs/alumina composites by electrical conductivity measurement2012

    • Author(s)
      Naoki Ueda, Tomohiko Yamakami, Tomohiro Yamaguchi, Morinobu Endo, Naoto Saito, Seiichi Taruta
    • Organizer
      Fourth International Congress on Ceramics
    • Place of Presentation
      Sheraton Chicago Hotel & Towers (Chicago, Illinois, USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Influence of acid-treatment of CNTs on microstructural development and mechanical properties of CNTs/alumina composites2011

    • Author(s)
      Ueda N, et al
    • Organizer
      Nanocarbon 2011
    • Place of Presentation
      ホテルメトロポリタン長野(長野市)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts2011

    • Author(s)
      Shimizu M, et al
    • Organizer
      Nanocarbon 2011
    • Place of Presentation
      ホテルメトロポリタン長野(長野市)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Biocompatibility and bone tissue compatibility of alumina ceramics reinforced with carbon nanotubes2011

    • Author(s)
      Ogihara N, et al
    • Organizer
      Nanocarbon 2011
    • Place of Presentation
      ホテルメトロポリタン長野(長野市)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Carbon nanofiber web for bone tissue regeneration2011

    • Author(s)
      Saito N, et al
    • Organizer
      Nanocarbon 2011
    • Place of Presentation
      ホテルメトロポリタン長野(長野市)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Eraluation of CNT toxicity in comparison to tattoo ink nanoparticles for use as a biomaterial2011

    • Author(s)
      Hara K, et al
    • Organizer
      Nanocarbon 2011
    • Place of Presentation
      ホテルメトロポリタン長野(長野市)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] カーボンブラック複合ハイドロキシアパタイトセラミックスの作製と性質2011

    • Author(s)
      森口悠平, 他
    • Organizer
      第42回中部化学関係学協会支部連合秋季大会
    • Place of Presentation
      信州大学工学部(長野市)
    • Year and Date
      2011-11-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 金属アルコキシドを用いたカーボンナノファイバーへのアルミナ粒子の析出2011

    • Author(s)
      荒井善生, 他
    • Organizer
      第27回日本セラミックス協会関東支部研究発表会
    • Place of Presentation
      千葉大学(千葉市)
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] CNTs複合アルミナセラミックスの微構造および機械的性質に与えるCNTs繊維径の影響2011

    • Author(s)
      植田直樹, 他
    • Organizer
      日本セラミックス協会第24回秋季シンポジウム
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] カーボンナノファイバー複合SiCのゲルキャスティングによる作製と性質2011

    • Author(s)
      徐国勝, 他
    • Organizer
      日本セラミックス協会第24回秋季シンポジウム
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Remarks] 信州大学 研究者総覧

    • URL

      http://soar-rd.shinshu-u.ac.jp/profile/ja.OacaZVkh.html

    • Related Report
      2014 Annual Research Report
  • [Patent(Industrial Property Rights)] 生体活性アルミナの製造方法、アパタイト-アルミナ複合材料の製造方法2013

    • Inventor(s)
      樽田誠一,齋藤直人,薄井雄企,青木 薫,植田直樹,福井亮太
    • Industrial Property Rights Holder
      信州大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-148825
    • Filing Date
      2013-07-17
    • Related Report
      2013 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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