| Project/Area Number |
23380116
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General fisheries
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| Research Institution | International Christian University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAGAWA Hirohiko 宮崎大学, 農学部, 教授 (60169381)
SOYANO Kiyoshi 長崎大学, 水産・環境科学総合研究科(環シナ), 教授 (80260735)
YOSHIZAKI Goro 東京海洋大学, 海洋科学部, 准教授 (70281003)
NUNOSHIBA Tatsuo 国際基督教大学, 教養学部, 教授 (10270802)
HAYAKAWA Yoichi 国際基督教大学, アーツ・サイエンス学科, 研究員 (50384011)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2011: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Keywords | 生殖腺刺激ホルモン / 組換えホルモン / バイオテクノロジー / 魚類 / 性成熟促進 / 養殖 |
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| Research Abstract |
Knowledge of reproductive endocrinology of fish is essential for the efficient aquaculture. However, information on the function of pituitary gonadotropin of fish is not clearly known because of unavailability of the hormones. Therefore, we started a project to produce recombinant fish gonadotropins biotechnologically using silkworm larvae as a host and distribute the hormones to fish biologists for their research. In the present study, we investigated the efficiency of the hormone production, method of hormone purification, stability of administered hormones in fish, biological activities of hormones, and sensitivity to the hormones in recipient fish.
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