| Project/Area Number |
23390171
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Teikyo University (2013, 2015)
Tohoku University (2011-2012, 2014) |
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Principal Investigator |
Asayama Kei 帝京大学, 医学部, 講師 (80431518)
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| Co-Investigator(Kenkyū-buntansha) |
KIKUYA Masahiro 東北大学, 東北メディカル・メガバンク機構, 准教授 (80361111)
TATSUTA Nozomi 東北大学, 医学系研究科, 助教 (40547709)
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| Co-Investigator(Renkei-kenkyūsha) |
IMAI Yutaka 東北大学, 薬学研究科, 教授 (40133946)
OHKUBO Takayoshi 帝京大学, 医学部, 教授 (60344652)
SATOH Hiroshi 東北大学, 医学系研究科, 名誉教授 (40125571)
NAKAI Kunihiko 東北大学, 医学系研究科, 教授 (00291336)
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| Research Collaborator |
Staessen Jan A.
Thijs Lutgarde
保坂 実樹
佐藤 倫広
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| Project Period (FY) |
2011-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 家庭血圧 / DOHaD / 母乳栄養 / 母子保健 / 妊娠高血圧症候群 / 自由行動下血圧 / メタ解析 / 老研式活動能力指標 / 高次生活機能 / 小児家庭血圧 / フィールド調査 / 小児 / 社会医学 |
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| Outline of Final Research Achievements |
The Tohoku Study of Child Development (TSCD) is a prospective birth cohort consisted of two areas in Japan. We measured home blood pressure of the mothers and of their 7-year-old children who participated in the TSCD for 2 weeks. We found that (1) breastfeeding has a protective effect against elevated blood pressure even in young children, and subtle, but important, differences were precisely detected by self-measurements performed at home, and (2) maternal pregnancy-induced hypertension (PIH) did not affect home blood pressure in offspring, but strongly affected maternal home blood pressure even 7 years after giving birth. From the longitudinal Ohasama cohort study, impacts of partial white-coat hypertension as well as partial masked hypertension for stroke risk were comparable to those of complete masked hypertension or sustained hypertension. Based on these 2 studies, we have unveiled further usefulness of self-measured home blood pressure.
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