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The model for fragility fracture predictions: a 15-year follow-up study of the Japanese Population-based Osteoporosis (JPOS) Cohort Study.

Research Project

Project/Area Number 23390180
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionOsaka Medical College (2013)
Kinki University (2011-2012)

Principal Investigator

TAMAKI Junko  大阪医科大学, 医学部, 教授 (90326356)

Co-Investigator(Kenkyū-buntansha) IKI Masayuki  近畿大学, 医学部, 教授 (50184388)
SATO Yuho  仁愛大学, 生活科学学科, 教授 (10337115)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥12,480,000 (Direct Cost: ¥9,600,000、Indirect Cost: ¥2,880,000)
Keywords骨折 / 骨粗鬆症 / リスク評価 / 無作為標本 / 前向きコホート研究 / 地域保健
Research Abstract

We conducted the 15-year follow-up survey of JPOS Cohort Study.
Bone microarchitecture assessed by trabecular bone score (TBS) could predict for 10-year risk of major osteoporotic fractures independently of FRAX® score. Neither bone turnover markers were associated with the fracture risk independently of FRAX® score. Lumbar spine bone mineral density, TBS, bone turnover markers, previous fragility fractures, and secondary osteoporosis were significantly associated with a risk of vertebral fractures.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (13 results)

All 2014 2013 2012 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results) Presentation (6 results) Remarks (2 results)

  • [Journal Article] Cohort Profile : The Japanese Population-based Osteoporosis (JPOS) Cohort Study2014

    • Author(s)
      Iki M, Tamaki J, Sato Y, Morita A, Ikeda Y, Kajita E, Nishino H, Akiba T, Matsumoto T, Kagamimori S, Kagawa Y, Yoneshima H
    • Journal Title

      International Journal of Epidemiology

      Volume: 84 Issue: 2 Pages: 1-10

    • DOI

      10.1093/ije/dyu084

    • Related Report
      2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Trabecular bone score (TBS) predicts vertebral fractures in Japanese women over 10 years independently of bone density and prevalent vertebral deformity : the Japanese Population-Based Osteoporosis (JPOS) cohort study2014

    • Author(s)
      Iki M, Tamaki J, Kadowaki E, Sato Y, Dongmei N, Winzenrieth R, Kagamimori S, Kagawa Y, Yoneshima H
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 29 Issue: 2 Pages: 399-407

    • DOI

      10.1002/jbmr.2048

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Trabecular bone score (TBS) predicts vertebral fractures in Japanese women over 10 years independently of bone density and prevalent vertebral deformity: the Japanese Population-Based Osteoporosis (JPOS) cohort study.2014

    • Author(s)
      Iki M, Tamaki J, Kadowaki E, Sato Y, Dongmei N, Winzenrieth R, Kagamimori S, Kagawa Y, Yoneshima H.
    • Journal Title

      J Bone Miner Res.

      Volume: 29巻 Pages: 399-407

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical markers for bone turnover predict risk of vertebral fractures in postmenopausal women over 10 years : the Japanese Population-based Osteoporosis (JPOS) Cohort Study2013

    • Author(s)
      Tamaki J, Iki M, Kadowaki E, Sato Y, Chiba Y, Akiba T, Matsumoto T, Nishino H, Kagamimori S, Kagawa Y, Yoneshima H; JPOS Study Group
    • Journal Title

      Osteoporosis International

      Volume: 24 Issue: 3 Pages: 887-897

    • DOI

      10.1007/s00198-012-2106-7

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Biochemical markers for bone turnover predict risk of vertebral fractures in postmenopausal women over 10 years: the Japanese Population-based Osteoporosis (JPOS) Cohort Study.2013

    • Author(s)
      Tamaki J, Iki M, Kadowaki E, Sato Y, Chiba Y, Akiba T, Matsumoto T, Nishino H, Kagamimori S, Kagawa Y, Yoneshima H; JPOS Study Group.
    • Journal Title

      Osteoporos Int.

      Volume: 24巻 Pages: 887-897

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 無作為抽出標本の15年間追跡データを用いたFRAX[〇!R]の有用性の検討-JPOS Cohort Study2014

    • Author(s)
      玉置淳子
    • Organizer
      第24回疫学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2014-01-24
    • Related Report
      2013 Final Research Report
  • [Presentation] 体脂肪分布パターンと糖尿病および心血管疾患のリスク要因との関連 : 二重エネルギーX線吸収法による検討2013

    • Author(s)
      冬海
    • Organizer
      第23回日本疫学会学術総会
    • Place of Presentation
      吹田市
    • Year and Date
      2013-01-26
    • Related Report
      2013 Final Research Report
  • [Presentation] 閉経女性における体組成と骨密度の関連-JPOS Study 15 年次調査による閉経後年数別検討2012

    • Author(s)
      玉置淳子
    • Organizer
      第71回日本公衆衛生学会
    • Place of Presentation
      山口市
    • Year and Date
      2012-10-26
    • Related Report
      2013 Final Research Report
  • [Presentation] 無作為抽出標本の15年間追跡データを用いたFRAX®の有用性の検討-JPOS Cohort Study

    • Author(s)
      玉置淳子、伊木雅之、由良晶子、梶田悦子、佐藤裕保、鏡森定信、香川芳子、米島秀夫、JPOS Study Group.
    • Organizer
      第24回疫学会総会
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 閉経女性における体組成と骨密度の関連-JPOS Study 15年次調査による閉経後年数別検討

    • Author(s)
      玉置淳子、伊木雅之、冬海、由良晶子、甲田勝康、藤田裕規、佐藤裕保、梶田悦子、中谷芳美、鏡森定信、香川芳子、米島秀夫
    • Organizer
      第71回日本公衆衛生学会
    • Place of Presentation
      山口市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 体脂肪分布パターンと糖尿病および心血管疾患のリスク要因との関連:二重エネルギーX線吸収法による検討

    • Author(s)
      冬海、甲田勝康、玉置淳子、伊木雅之、鏡森定信、香川芳子、米島秀夫
    • Organizer
      第23回日本疫学会学術総会
    • Place of Presentation
      吹田市
    • Related Report
      2012 Annual Research Report
  • [Remarks] JPOS 研究のホームページを作成した

    • URL

      http://www.med.kindai.ac.jp/pubheal/jpos/index.html

    • Related Report
      2013 Final Research Report
  • [Remarks] The JPOS Study

    • URL

      http://www.med.kindai.ac.jp/pubheal/jpos/index.htm

    • Related Report
      2013 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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