| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2013: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2012: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
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| Research Abstract |
In this project we analyzed how chronic inflammation that is initiated in obese adipose tissue affects the cardiovascular system in metabolic syndrome. We found that saturated fatty acids that are released from obese adipose tissue promote inflammation in the cardiovascular system ("fat-heart, fat-vessel crosstalk"). We also found that the heart and kidneys interact with each other in response to cardiac stress, and this interaction ("cardiorenal crosstalk") is important for the maintenance of cardiac homeostasis.
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