| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Outline of Final Research Achievements |
The results of this research having the purpose of developing novel caries treatment materials, method based on dentin remineralization technology and dentin regeneration technology are as follows; Firstly, the mineral induction ability of CMET was confirmed and the high remineralization activity and the long-term durability at the adhesion interface of CMET containing adhesive materials were clarified. Furthermore, it was demonstrated that phosphohporyn RGD-peptides promoted odontoblast-differentiation in vitro and the reparative dentin formation in vivo. From these results, it was suggested the high possibility of these materials as novel caries treatment materials.
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