| Project/Area Number |
23390445
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOYANO Kiyoshi 九州大学, 大学院・歯学研究院, 教授 (50195872)
OGINO Yoichiro 九州大学, 大学院・歯学研究院, 助教 (50380431)
神野 洋平 九州大学, 歯学研究科(研究院), 助教 (40507779)
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| Co-Investigator(Renkei-kenkyūsha) |
SUZUKI Yumiko 九州大学, 大学病院, 学術研究員 (20432916)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Keywords | 骨増生 / インプラント / 骨補填材 / GBR / 国際研究者交流（米国） |
|---|
| Research Abstract |
The outcome of prosthodontic treatments depends upon both quality and quantity of the alveolar or jaw bone. Thus, bone augmentation procedure as a preprosthodontic treatment is considered to be important and the development of the patient-friendly procedure has been expected. In the present study, we aimed at the establishment of novel procedure by which accelerated healing of both soft and hard tissue could be accomplished using statins, a group of drugs for cholesterol-lowering. As a result, using sheet-like poly (lactide-co-glycolide) with statin both soft and hard tissue healing could be enhanced. In addition, we developed novel statin-impregnated apatite material by which accelerated bone healing was observed.
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