The prevalenc and associated risk factors for chronic kidney fosease or reduced kidney function in Bangladesh rural.
| Project/Area Number |
23406029
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Kidney internal medicine
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| Research Institution | Ibaraki Prefectural University of Health Science |
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Principal Investigator |
YAMAGUCHI Naoto 茨城県立医療大学, 保健医療学部, 教授 (40239900)
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| Co-Investigator(Kenkyū-buntansha) |
JESMIN Subrina 筑波大学, 医学医療系, 助教 (60374261)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2011: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Keywords | 慢性腎臓病 / メタボリック症候群 / 東南アジア / 性差 / 閉経 / 地域横断的疫学調査 / 血管内皮増殖因子 / 推算GFR値 / VEGF / 糖尿病 / 低HDL血症 / ＶＥＧＦ / 慢性腎臓病(CKD) / eGFR |
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| Research Abstract |
The aim of this study is to reveal the prevalence of chronic kidney disease or reduced kidney function (CKD: eGFR<60ml/min/1.73m2) and to estimate its association with component of metabolic syndrome (MS), in view of differences between subgroups divided by gender or pre-/post-menopausal status in Bangladesh rural, based on a community based cross-sectional survey among 1,701 people (men166, women1,535), with 446 serum samples of creatinine. The total prevalence of CKD is 30% (men 25%, pre-menopausal 28%, and post-menopausal women 45%, p<0.05). Prevalence of CKD in patients with MS was higher than that in people without MS (p<0.01). Hyperglycemia and higher gravidity were well correlated with CKD in pre-menopausal women, and hyperlipidemia was correlated with CKD in post-menopausal. The mean level of eGFR was the lowest in post-menopausal among the subgroups of gender or menopausal status.These data suggest that slowing the rise in MS may contribute to prevent CKD in this area.
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Report
(4 results)
Research Products
(37 results)
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[Presentation] Assessment of circulatory endothelin-a level among pre- and post- menopausal rural women in Bangladesh: result from a population-based study.2013
Author(s)
Khatun MT, Jesmin S, Rahman A, Habib AA, Islam M, Akter S, Shimojo N, Kimura S, Okazaki O, Moroi M, Yamaguchi N, et al.
Organizer
Thirteenth International conference on endothelin
Place of Presentation
筑波大学東京
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[Book] Chapter 12: Development of therapeutic strategy to restore coronary microcirculation and vascular endothelial growth factor signaling cascade in diabetes mellitus. In Diabetes Mellitus and Human Health Care, edited by george A, Augustine R.2013
Author(s)
Jesmin S, Rahman A, Manum AA, Akter S, Iwashima Y, Shimojo N, Yamaguchi N, Hiroaki M, Mizutani T, Moroi M
Total Pages
12
Publisher
CBC Press: ISBN 978-19268-95765
Related Report
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