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Knowledge Discovery in Multivariate Clinical Time Series based on Hierarchical Structure Modeling

Research Project

Project/Area Number 23500190
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Intelligent informatics
Research InstitutionDoshisha University

Principal Investigator

OHSAKI Miho  同志社大学, 理工学部, 准教授 (30313927)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords知識発見 / 多変量時系列 / 検査治療履歴 / 予後予測
Research Abstract

It has been required to automatically discover useful knowledge for symptom recognition and treatment in clinical data on chronic disease, which is a set of multivariate time series. This research project aims to develop methods of modeling, feature extraction, and prediction of symptoms for clinical examination and treatment histories on chronic hepatitis C. We described symptoms by hierarchically applying autoregressive models and autoregressive conditional heteroscedastic models, extracted features using the modeling results, and derived knowledge on how much measurements are necessary for symptom recognition based on the model orders. In addition to that, we developed a system to predict the degree of liver damage using kernel logistic regression and proposed a new classifier that is based on kernel logistic regression and trains itself with discriminative learning.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (23 results)

All 2013 2012

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (17 results)

  • [Journal Article] C型慢性肝炎の肝線維化ステージ推定を目指した検査値時系列の動的特徴量の提案2013

    • Author(s)
      大崎美穂,宮崎淳文,谷口恵梨,片桐滋,横井英人,高林克日己
    • Journal Title

      医療情報学

      Volume: vol.33,no.2 Pages: 79-98

    • NAID

      130004700964

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] C型慢性肝炎の肝線維化ステージ推定を目指した検査値時系列の動的特徴量の提案2013

    • Author(s)
      大崎美穂,宮崎淳文,谷口恵梨,片桐滋,横井英人,高林克日己
    • Journal Title

      医療情報学

      Volume: vol.33, no.2 Pages: 79-98

    • NAID

      130004700964

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 音量の好みを用いた評価値予測によるインタラクティブECフィッティングの改善手法2012

    • Author(s)
      大崎美穂
    • Journal Title

      知能と情報

      Volume: vol.24,no.2 Pages: 680-690

    • NAID

      130002096911

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Feature Extraction for the Prediction of Liver Fibrosis Stages in Chronic Hepatitis C2012

    • Author(s)
      Akifumi Miyazaki, Miho Ohsaki, Eri Taniguchi, Shigeru Katagiri, Hideto Yokoi, Katsuhiko Takabayashi
    • Journal Title

      Proceedings of IEEE Region 10 Conference

      Volume: TENCON-2012 Pages: 1-5

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Application of Kernel Logistic Regression to the Prediction of Liver Fibrosis Stages in Chronic Hepatitis C2012

    • Author(s)
      Kenji Matsuda, Miho Ohsaki, Shigeru Katagiri, Hideto Yokoi, Katsuhiko Takabayashi
    • Journal Title

      Proceedings of Joint International Conference on Soft Computing and Intelligent Systems and International Symposium on Advanced Intelligent Systems

      Volume: SCIS&ISIS-2012 Pages: 780-784

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A Feature Consisting of Mean, Standard Deviation, and LPC Cepstrum for the Prediction of Liver Fibrosis Stages in Chronic Hepatitis C2012

    • Author(s)
      Akifumi Miyazaki, Miho Ohsaki, Eri Taniguchi, Shigeru Katagiri, Hideto Yokoi, Katsuhiko Takabayashi
    • Journal Title

      Proceedings of Joint International Conference on Soft Computing and Intelligent Systems and International Symposium on Advanced Intelligent Systems

      Volume: SCIS&ISIS-2012 Pages: 2295-2298

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] C型慢性肝炎の肝線維化ステージ推定を目指した検査値時系列区分化の影響の検証2013

    • Author(s)
      安本亮介,宮崎淳文,大崎美穂,片桐滋,横井英人,高林克日己
    • Organizer
      情報処理学会研究報告
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ推定を目指したスペクトラム推定量に基づく特徴量の比較2013

    • Author(s)
      宮崎淳文,大崎美穂,安本亮介,片桐滋,横井英人,高林克日己
    • Organizer
      情報処理学会研究報告
    • Related Report
      2013 Final Research Report
  • [Presentation] Modeling and Feature Extraction of Clinical Time Series Aiming at the Diagnosis Prediction of Chronic Hepatitis C2013

    • Author(s)
      Akifumi Miyazaki, Miho Ohsaki, Shigeru Katagiri
    • Organizer
      Joint Symposium between Chonnam National University and Doshisha University
    • Related Report
      2013 Final Research Report
  • [Presentation] ファジィアプローチとベイズアプローチの関係の調査2013

    • Author(s)
      安本亮介,大崎美穂
    • Organizer
      第29回ファジィシステムシンポジウム
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ予測への取り組み2013

    • Author(s)
      大崎美穂,宮崎淳文,松田健司,片桐滋,横井英人,高林克日己
    • Organizer
      パーティクルフィルタ研究会
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ推定を目指したスペクトラム推定量に基づく特徴量の比較2013

    • Author(s)
      宮崎淳文,大崎美穂,安本亮介,片桐滋,横井英人,高林克日己
    • Organizer
      情報処理学会研究報告,vol. 2013-BIO-36,no. 13,pp.1-6
    • Place of Presentation
      東京工業大学 大岡山キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ推定を目指した検査値時系列区分化の影響の検証2013

    • Author(s)
      安本亮介,宮崎淳文,大崎美穂,片桐滋,横井英人,高林克日己
    • Organizer
      情報処理学会研究報告,vol. 2013-BIO-36,no. 14,pp.1-6
    • Place of Presentation
      東京工業大学 大岡山キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] Modeling and Feature Extraction of Clinical Time Series Aiming at the Diagnosis Prediction of Chronic Hepatitis C2013

    • Author(s)
      Akifumi Miyazaki, Miho Ohsaki, Shigeru Katagiri
    • Organizer
      Joint Symposium between Chonnam National University and Doshisha University, no.PD14
    • Place of Presentation
      Kyotanabe Campus, Doshisha University
    • Related Report
      2013 Annual Research Report
  • [Presentation] A Feature Consisting of Mean, Standard Deviation, and LPC Cepstrum for the Prediction of Liver Fibrosis Stages in Chronic Hepatitis C2012

    • Author(s)
      Akifumi Miyazaki, Miho Ohsaki, Eri Taniguchi, Shigeru Katagiri, Hideto Yokoi, Katsuhiko Takabayashi
    • Organizer
      Joint International Conference on Soft Computing and Intelligent Systems and International Symposium on Advanced Intelligent Systems SCIS&ISIS-2012
    • Related Report
      2013 Final Research Report
  • [Presentation] Application of Kernel Logistic Regression to the Prediction of Liver Fibrosis Stages in Chronic Hepatitis C2012

    • Author(s)
      Kenji Matsuda, Miho Ohsaki, Shigeru Katagiri, Hideto Yokoi, Katsuhiko Takabayashi
    • Organizer
      Joint International Conference on Soft Computing and Intelligent Systems and International Symposium on Advanced Intelligent Systems SCIS&ISIS-2012
    • Related Report
      2013 Final Research Report
  • [Presentation] Feature Extraction for the Prediction of Liver Fibrosis Stages in Chronic Hepatitis C2012

    • Author(s)
      Akifumi Miyazaki, Miho Ohsaki, Eri Taniguchi, Shigeru Katagiri, Hideto Yokoi, Katsuhiko Takabayashi
    • Organizer
      IEEE Region 10 Conference TENCON-2012
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ予測に適する特徴量の検討2012

    • Author(s)
      谷口恵梨,大崎美穂,片桐滋,横井英人,高林克日己
    • Organizer
      第39回知能システムシンポジウム
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ予測に役立つ特徴量の提案2012

    • Author(s)
      谷口恵梨,大崎美穂,片桐滋
    • Organizer
      第32回東海ファジィ研究会
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ分類手法の比較2012

    • Author(s)
      松田健司,大崎美穂,片桐滋
    • Organizer
      第32回東海ファジィ研究会
    • Related Report
      2013 Final Research Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ分類手法の比較2012

    • Author(s)
      松田健司,大崎美穂,片桐滋
    • Organizer
      第32回東海ファジィ研究会
    • Place of Presentation
      日間賀島公民館(知多郡)
    • Related Report
      2011 Research-status Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ予測に役立つ特徴量の提案2012

    • Author(s)
      谷口恵梨,大崎美穂,片桐滋
    • Organizer
      第32回東海ファジィ研究会
    • Place of Presentation
      日間賀島公民館(知多郡)
    • Related Report
      2011 Research-status Report
  • [Presentation] C型慢性肝炎の肝線維化ステージ予測に適する特徴量の検討2012

    • Author(s)
      谷口恵梨,大崎美穂,片桐滋,横井英人,高林克日己
    • Organizer
      第39回知能システムシンポジウム
    • Place of Presentation
      千葉大学 西千葉キャンパス けやき会館(千葉市)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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