A study of practical suppression method of alternans using both mathematical and animal models.
| Project/Area Number |
23500524
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
YAZAWA Toru 首都大学東京, 理工学研究科, 助教 (30106603)
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| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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|---|
| Keywords | 交互脈 / Alternans / 高カリウム / モデル / 心臓 / 不整脈 / イオン / 数理モデル / 生理学実験 / 甲殻類 / 動物モデル |
|---|
| Research Abstract |
Alternans is called as harbinger of death rhythm, being well observable in a patient of ischemic heart disease. Mathematical model used my crab-heart data as a parameter of synaptic potentials. Then, the model could induce alternans, when extracellular potassium (K+) concentration was increased. I concluded that ionic concentration of K+ in the tissue fluid is a key factor to suppress generation of alternans.
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Report
(4 results)
Research Products
(54 results)
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[Journal Article] Measurement of Stress Using DFA Heartbeat Analysis2013
Author(s)
Yazawa, T., Hutapea, A. M., Otomura, Y., Sagawa, K., Yamada, Y., Suzuki, T., and Katsuyama, T
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Journal Title
Proceedings of The World Congress on Engineering and Computer Science 2013
Pages: 596-603
Related Report
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[Journal Article] DFA of Cardiac and Psychological Abnormality: A Test of Quantification Method on Models and Humans.2013
Author(s)
Yazawa, T., Hutapea, A. M., Shimoda, Y., Otomura, Y., Sagawa, K., Yamada, Y., and Suzuki, T.
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Journal Title
Proceedings of The 17th World Multi-Conference on Systemics, Cybernetics and Informatics
Volume: -
Pages: 58-63
Related Report
Peer Reviewed
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[Journal Article] Measurement of Stress Using DFA Heartbeat Analysis.2013
Author(s)
Yazawa, T., Hutapea, A. M., Otomura, Y., Sagawa, K., Yamada, Y., Suzuki, T., and Katsuyama, T.
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Journal Title
Proceedings of The World Congress on Engineering and Computer Science 2013
Volume: -
Pages: 596-603
Related Report
Peer Reviewed
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