| Project/Area Number |
23500594
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Satoshi 鹿児島大学, 医学部・歯学部附属病院, 講師 (00343369)
YOSHIDA Akira 鹿児島大学, 医歯学総合研究科, 助教 (40347109)
KAWAHIRA Kazumi 鹿児島大学, 医歯学総合研究科, 客員研究員 (20117493)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | マイクロダイアリシス / 神経伝達物質 / 脳の可塑性 / 運動療法 / 機能回復 |
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| Research Abstract |
Extracellular concentrations of monoamines were investigated in the striatum, hippocampus, primary cortex, hindlimb region and ventral tegmental area using microdialysis technique. We confirmed that monoamine levels were increased during treadmill running. Nerve activity becomes active by compulsorily exercise, but is not efficient for the functional recovery. We pay our attention to change of dopamine levels as the reward material and examine a method to restore motor function effectively.
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