Factors of Well being and DQOL which influence on adherance of management of type 2 diabetes

• Project/Area Number: 23500856
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied health science
• Research Institution: Toho University (2012-2014); Juntendo University (2011)
• Principal Investigator: HIROSE Takahisa 東邦大学, 医学部, 教授 (40384119)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 糖尿病教育入院 / 2型糖尿病 / QOL / 睡眠 / 昼夜逆転 / 糖尿病 / 教育入院 / DQOL / HbA1c / 生活リズム / 睡眠の量 / 睡眠の質

Outline of Final Research Achievements

We have performed several questionair on QOL to about 300 type 2 diabetic patients. MEQ correlated positively with age, and high-density lipoprotein cholesterol (HDL-C), and negatively with glycated hemoglobin (HbA1c) and PSQI. Multivariate regression analysis showed that MEQ was significantly associated with HbA1c and HDL-C. In addition, we classified the study patients into three groups: ‘morning type’, ‘neither type’ and ‘evening type’ according to the sum of the MEQ score, and analyzed the difference between morning type (n = 32) and evening type (n = 11). We found that HbA1c, low-density lipoprotein cholesterol and PSQI of the morning type group were significantly lower than those of the evening type group.
Our study suggests that‘eveningness’ type male Japanese patients with type 2 diabetes suffer inadequate glycemic control.

Research Products

• [Journal Article] Reliability and validity of the Japanese version of the Diabetes Quality-Of-Life questionnaire for Japanese patients with type 2 diabetes mellitus. (2014)
  • Author(s): Sato F, Mita T, Yamamoto R, Hirose T, Ito C, Tamura Y, Yokota A, Someya Y, Uchida T, Uchino H, Kawamori R, Gosho M, Ohmura C, Kanazawa A, Watada H
  • Journal Title: Diabetology International Volume: 5 Issue: 1 Pages: 21-29
  • DOI: 10.1007/s13340-013-0125-z
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Morningness & eveningness questionnaire score correlates with glycated hemoglobin in middle-aged male workers with type 2 diabetes mellitus (2013)
  • Author(s): Iwasaki M, Hirose T, Mita T, Sato F, Ito C, Yamamoto R, Someya Y, Yoshihara T, Tamura Y, Kanazawa A, Kawamori R, Fujitani Y, Watada H
  • Journal Title: Journal of Diabetes Investigation Volume: 4 Issue: 4 Pages: 376-381
  • DOI: 10.1111/jdi.12047
  • Peer Reviewed
• [Presentation] 2型糖尿病患者における糖尿病の心理と睡眠障害の関わりについての検討
  • Author(s): 佐藤文彦ほか
  • Organizer: 第54回日本糖尿病学会年次学術総会
  • Place of Presentation: 札幌
• [Presentation] Diabetes quality of life (DQOL) の翻訳と計量心理学的検討
  • Author(s): 山本理沙子ほか
  • Organizer: 第54回日本糖尿病学会年次学術総会
  • Place of Presentation: 札幌
• [Presentation] The Diabetes Family Behavior Checklist (DFBC)の翻訳と計量心理学的検討
  • Author(s): 伊藤千春ほか
  • Organizer: 第54回日本糖尿病学会年次学術総会
  • Place of Presentation: 札幌