| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Research Abstract |
Biomethylation of arsenic is usually considered as a detoxification of arsenic because toxicity of most organic methylated arsenic is much less than that of inorganic arsenic. To develop an effective technology for conversion of inorganic arsenic to arsenobetaine (AB) by using microorganisms, we have searched for microorganisms that have the ability to methylate arsenic that are adequately applicable for the detoxification process. As a result, we have successfully isolated a strain, Cellulomonas sp. strain K63 that has arsenic methylation ability from the soil. In this study, the arsenic methylation characteristics of strain K63 were evaluated. The results suggest that strain K63 is a microorganism with arsenic methylation ability that is sufficient for use in detoxification processes, and further suggests that if the conversion efficiency to AB can be improved, a technology for restoration of arsenic to nature after detoxification using microorganisms can be established.
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