| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
Synchronous oscillatory activity is common in the olfactory behavior of both vertebrates and invertebrates. In the terrestrial slugs, periodic oscillation is recorded from the surface of the laminar structure of olfactory center, procerebrum (PC) and its frequency changes are suggested to encode the olfactory information and memory. Gamma-aminobutyric acid (GABA) neurons are known to inhibitory neurons as a kernel of rhythm generation in oscillatory networks of vertebrate. In the present study, we found that GABAergic neuron has a role to play as an excitatory modulator in the PC oscillatory network of the slugs. This observation and the conclusion have been supported by the pharmacological study in reconstructed oscillatory networks of cultured PC neurons.
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