| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
By disturbance of the signal transduction systems for environmental signals, we have enabled induced production of nectriapyrones and tenuazonic acid in the rice blast fungus. In contrast, epigenetic control compounds could not cause induced production of these secondary metabolites. We found that the induced production of tenuazonic acid is caused via a LaeA ortholog, a global regulator of fungal secondary metabolism. We have succeeded in identifying the biosynthetic gene for nectriapyrones and tenuazonic acid and revealed that these compounds are not essential for infection of the rice blast fungus. Tenuazonic acid showed rice blast disease suppression activity.
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