Intracellular transport of phospholipids
| Project/Area Number |
23590080
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biological pharmacy
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| Research Institution | Kyushu University |
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Principal Investigator |
KUGE Osamu 九州大学, 理学(系)研究科(研究院), 教授 (30177977)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 生体膜 / リン脂質 / 細胞生物学 / 細胞内輸送 / 酵母 |
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| Research Abstract |
Intracellular transport of phospholipids is an essential event for the biogenesis of functional biological membranes. However, the transport processes are largely unknown with respect to mechanisms, genes and gene products involved. In this study I tried to identify novel genes involved in the phospholipids transport or phospholipid metabolism in yeast, and identified two genes that probably functioned in phospholipid transport to mitochondrial inner membrane, and one gene that was involved in the expression of a phospholipid metabolism gene, PSD2.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria2013
Author(s)
Y. Tamura, Y. Harada, S. Nishikawa, K. Yamano, M. Kamiya, T. Shiota, T. Kuroda, O. Kuge, H. Sesaki, K. Imai, K. Tomii, and T. Endo
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Journal Title
Cell Metab.
Volume: 17
Issue: 5
Pages: 709-718
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria.2013
Author(s)
Tamura Y, Harada Y, Nishikawa S, Yamano K, Kamiya M, Shiota T, Kuroda T, Kuge O, Sesaki H, Imai K, Tomii K, Endo T.
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Impaired retrograde membrane traffic through endosomes in a mutant CHO cell defective in phosphatidylserine synthesis.2012
Author(s)
Lee, S., Uchida1, Y., Emoto, K., Umeda, M., Kuge, O., Taguchi, T., Arai, H
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Journal Title
Genes to Cells
Volume: 17
Issue: 8
Pages: 728-36
DOI
Related Report
Peer Reviewed
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