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Analysis of novel chemokine receptor variant in cancer-associated inflammatory microenvironment

Research Project

Project/Area Number 23590406
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Human pathology
Research InstitutionYokohama City University

Principal Investigator

FURUYA Mitsuko  横浜市立大学, 医学部, 准教授 (10361445)

Co-Investigator(Kenkyū-buntansha) TANAKA Reiko  千葉大学, 真菌医学研究センター, 助教 (60143319)
AOKI Ichiro  横浜市立大学, 医学研究科, 教授 (00184028)
Co-Investigator(Renkei-kenkyūsha) MIYAGI Etsuko  横浜市立大学, 附属病院, 准教授 (40275053)
MIYAGI Yohei  神奈川県立がんセンター, がん分子病態研究部門, 部門長 (00254194)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords卵巣癌 / 炎症 / ケモカイン / 炎症性微小環境 / シグナル / 発癌 / 人体病理
Research Abstract

We examined pathophysiology of impaired CXCR3 signaling in endometriosis-associated ovarian cancer (EAOC) under IFN-g enriched microenvironment.
The expression of CXCL4, a ligand of CXCR3-B, was gradually suppressed as cancer developed from endometriosis lesion. We confirmed that the responsible cell type expressing CXCL4 was macrophage. Interestingly, infiltrating macrophages in endometriosis were CD68 (+) CXCL4 (+) whereas those in EAOC were CD163 (+) CXCL4 (-). Furthermore, we found that suppressor of cytokine signaling (SOCS) was severely suppressed in these IFN-g-high EAOC.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (75 results)

All 2014 2013 2012 2011 Other

All Journal Article (29 results) (of which Peer Reviewed: 29 results) Presentation (42 results) (of which Invited: 2 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Intratumoral peripheral small papillary tuft (ITPSPT): A diagnostic clue of renal tumors associated with Birt-Hogg-Dubé syndrome.2014

    • Author(s)
      Kuroda N, Furuya M, Nagashima Y, Gotoda H, Moritani S, Kawakami F, Imamura Y, Bando Y, Takahashi M, Kanayama H, Ota S, Michal M, Hes O, Nakatani Y
    • Journal Title

      Ann Diagn Pathol

      Volume: 14 Issue: 3 Pages: 1092-9134

    • DOI

      10.1016/j.anndiagpath.2014.03.002

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Uterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCT) with Metastasis : Clinico- pathological Study of Two Cases2014

    • Author(s)
      Umeda S, Tateno M, Miyagi E, Sakurai K, Tanaka R, Tateishi Y, Tokinaga A, Ohashi K, Furuya M.
    • Journal Title

      Int J Clin Exp Pathol

      Volume: vol7 Pages: 1051-9

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Colonic Low Grade Endometrial Stromal Sarcoma and Orthotopic Endometrial Stromal Tumor with Limited Infiltration Sharing the JAZF1-SUZ12 Gene Fusion2014

    • Author(s)
      Tokinaga A, Furuya M, Niino H, Udaka N, Asai-Sato M, Sekido H, Miyagi E
    • Journal Title

      Pathol Int

      Volume: vol 64 Issue: 4 Pages: 178-182

    • DOI

      10.1111/pin.12151

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Radiologically Indeterminate Pulmonary Cysts in Birt-Hogg-Dubé Syndrome2014

    • Author(s)
      Onuki T, Goto Y, Kuramochi M, Inagaki M, Suzuki K, Bhunchet E, Tanaka R, Furuya M
    • Journal Title

      Ann Thoracic Surg

      Volume: vol 97 Issue: 2 Pages: 682-685

    • DOI

      10.1016/j.athoracsur.2013.05.120

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Whole exome sequencing revealed biallelic IFT122 mutations in a family with CED1 and recurrent pregnancy loss.2014

    • Author(s)
      Tsurusaki Y, Yonezawa R, Furuya M, Nishimura G, Pooh R, Nakashima M, Saitsu H, Miyake N, Saito S, Matsumoto N.
    • Journal Title

      Clin Genet.

      Volume: 85 Issue: 6 Pages: 592-594

    • DOI

      10.1111/cge.12215

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Uterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCT) with Metastasis: Clinicopathological Study of Two Cases.2014

    • Author(s)
      Umeda S, Tateno M, Miyagi E, Sakurai K, Tanaka R, Tateishi Y, Tokinaga A, Ohashi K, Furuya M.
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 7 Pages: 1051-1059

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Colonic Low Grade Endometrial Stromal Sarcoma and Orthotopic Endometrial Stromal Tumor with Limited Infiltration Sharing the JAZF1-SUZ12 Gene Fusion.2014

    • Author(s)
      Tokinaga A, Furuya M, Niino H, Udaka N, Sato-Asai M, Sekido H Miyagi E
    • Journal Title

      Pathol Int.

      Volume: 64 Pages: 178-184

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radiologically Indeterminate Pulmonary Cysts in Birt-Hogg-Dubé Syndrome.2014

    • Author(s)
      Onuki T, Goto Y, Kuramochi M, Inagaki M, Suzuki K, Bhunchet E, Tanaka R, Furuya M.
    • Journal Title

      Ann Thoracic Surg

      Volume: 97 Pages: 682-685

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multifocal and microscopic chromophobe renal cell carcinomatous lesions associated with 'capsulomas' without FCLN gene abnormality.2013

    • Author(s)
      Sugimoto K, Takasawa A, Ichimiya S, Murata M, Kimura H, Aoyama T, Gille JJ, Kuroda N, Shimizu H, Hasegawa T, Sawada N, Furuya M, Nagashima Y.
    • Journal Title

      Pathol Int.

      Volume: 60 Issue: 10 Pages: 510-515

    • DOI

      10.1111/pin.12099

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hepatocyte Nuclear Factor-1ΑInactivated Hepato- cellular Adenomas in Patient With Congenital Absence of The Portal Vein2013

    • Author(s)
      Tateishi Y, Furuya M, Kondo F, Okudela K, Umeda S, Ohashi K
    • Journal Title

      Pathol Int

      Volume: vol 63 Issue: 7 Pages: 358-363

    • DOI

      10.1111/pin.12072

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Unique Mutation, Accelerated mTOR Signaling and Angiogenesis in the Pulmonary Cysts of Birt-Hogg-Dubé Syndrome2013

    • Author(s)
      Nishii T, Tanabe M, Tanaka R, Matsuzawa T, Okudela K, Nozawa A, Nakatani Y, Furuya M
    • Journal Title

      Pathol Int

      Volume: vol 63 Issue: 1 Pages: 45-55

    • DOI

      10.1111/pin.12028

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] A case of synchronous mucinous metaplasia and neoplasia of the female genital tract without an STK11 or KRAS mutation2013

    • Author(s)
      Nagahama K, Yamanaka S, Nakayama T, Tokinaga A, Asai-Sato M, Miyagi E, Tanaka R, Furuya M
    • Journal Title

      Gynecol Oncol Case Rep

      Volume: vol 5 Pages: 4-5

    • DOI

      10.1016/j.gynor.2013.02.005

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Birt-Hogg-Dubé Syndrome2013

    • Author(s)
      Furuya M, Nakatani Y
    • Journal Title

      J Clin Pathol

      Volume: vol 66 Issue: 3 Pages: 178-188

    • DOI

      10.1136/jclinpath-2012-201200

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Multifocal and microscopic chromophobe renal cell carcinomatous lesions associated with 'capsulomas' without FCLN gene abnormality2013

    • Author(s)
      Sugimoto K, Takasawa A, Ichimiya S, Murata M, Kimura H, Aoyama T, Gille JJ, Kuroda N, Shimizu H, Hasegawa T, Sawada N, Furuya M, Nagashima Y
    • Journal Title

      Pathol Int.

      Volume: 63 Pages: 510-515

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hepatocyte Nuclear Factor-1Α Inactivated Hepatocellular Adenomas In Patient With Congenital Absence Of The Portal Vein2013

    • Author(s)
      Tateishi Y, Furuya M, Kondo F, Okudela K, Umeda S, Ohashi K
    • Journal Title

      Pathol Int.

      Volume: 63 Pages: 358-363

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unique Mutation, Accelerated mTOR Signaling and Angiogenesis in the Pulmonary Cysts of Birt-Hogg-Dubé Syndrome2013

    • Author(s)
      Nishii T, Tanabe M, Tanaka R, Matsuzawa T, Okudela K, Nozawa A, Nakatani Y, Furuya M
    • Journal Title

      Pathol Int.

      Volume: 63 Pages: 45-55

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of synchronous mucinous metaplasia and neoplasia of the female genital tract without an STK11 or KRAS mutation.2013

    • Author(s)
      Nagahama K, Yamanaka S, Nakayama T, Tokinaga A, Asai-Sato M, Miyagi E, Tanaka R, Furuya M.
    • Journal Title

      Gynecol Oncol Case Rep

      Volume: 5 Pages: 4-5

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Birt-Hogg-Dubé Syndrome.2013

    • Author(s)
      Furuya M, Nakatani Y.
    • Journal Title

      J Clin Pathol

      Volume: 66 Pages: 178-188

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ovarian Cancer Stroma: Pathophysiology and the Roles in Cancer Development2012

    • Author(s)
      Furuya M
    • Journal Title

      Cancers

      Volume: 4 Issue: 3 Pages: 701-724

    • DOI

      10.3390/cancers4030701

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Impaired CXCL4 Expression in Tumor-Associated Macrophages (TAMs) of Ovarian Cancers Arising in Endometriosis2012

    • Author(s)
      Furuya M, Tanaka R, Miyagi E, Kami D ,Nagahama K, Miyagi Y, Nagashima Y, Hirahara F, Inayama Y, Aoki I.
    • Journal Title

      Cancer Biol Ther

      Volume: 13 Issue: 8 Pages: 671-680

    • DOI

      10.4161/cbt.20084

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pulmonary cysts of Birt-Hogg-Dube syndrome : A clinicopathological and immunohistochemical study of 9 families2012

    • Author(s)
      Furuya Mitsuko
    • Journal Title

      American Journal of Surgical Pathology

      Volume: 36 Issue: 4 Pages: 589-600

    • DOI

      10.1097/pas.0b013e3182475240

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Unilateral glomerulocystic kidney disease associated with tuberous sclerosis complex in a neonate.2012

    • Author(s)
      Murakami A, Gomi K, Tanaka M, Ohyama M, Itani Y, Ishikawa H, Aida N, Furuya M, Tanaka Y.
    • Journal Title

      Pathol Int

      Volume: 62 Issue: 3 Pages: 209-215

    • DOI

      10.1111/j.1440-1827.2011.02777.x

    • NAID

      10031185191

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] FLCN gene-mutated renal cell neoplasms : Mother and daughter cases with a novel germline mutation2012

    • Author(s)
      Nagashima Y, Furuya M, Gotohda H, Takagi S, Hes O, Michal M, Grossmann P, Tanaka R, Nakatani Y, Kuroda N
    • Journal Title

      Int J Urol

      Volume: 19(5) Issue: 5 Pages: 468-470

    • DOI

      10.1111/j.1442-2042.2011.02945.x

    • NAID

      10030755007

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Identification of miR-30d as a novel prognostic maker of prostate cancer2012

    • Author(s)
      Kobayashi N, Uemura H, Nagahama K, Okudela K, Furuya M, Ino Y, Ito Y, Hirano H, Inayama Y, Aoki I, Nagashima Y, Kubota Y, Ishiguro H.
    • Journal Title

      Oncotarget

      Volume: 3 Pages: 1455-1471

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Expression of Angiotensin II receptor-like 1 (APJ) in the Placentas of Pregnancy-Induced Hypertension.2012

    • Author(s)
      Furuya M, Okuda M, Usui H, Takenouchi T, Kami D, Nozawa A, Shozu M, Umezawa A, Takahashi T, Aoki I.
    • Journal Title

      Int Gynecol Pathol

      Volume: 31 Issue: 3 Pages: 227-235

    • DOI

      10.1097/pgp.0b013e31823b6e71

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Differential Expression Patterns of CXCR3 Variants and Corresponding CXC Chemokines in Clear Cell Ovarian Cancers and Endometriosis.2011

    • Author(s)
      Furuya M, Yoneyama T, Miyagi E, Tanaka R, Nagahama K, Miyagi Y, Hirahara F, Inayama Y, Nagashima Y, Aoki I.
    • Journal Title

      Gynecol Oncol

      Volume: 122 Issue: 3 Pages: 684-655

    • DOI

      10.1016/j.ygyno.2011.05.034

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tumor Vasculature and Molecular Targeting Therapies.2011

    • Author(s)
      Furuya M, Nagahama K, Ishizu A, Otsuka N, Nagashima Y, Aoki I.
    • Journal Title

      Front Biosci

      Volume: 3 Pages: 549-561

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Disrupted Balance of Angiogenic and Antiangiogenic Signalings in Preeclampsia.2011

    • Author(s)
      Furuya M, Kurasawa K, Nagahama K, Kawachi K, Nosawa A, Takahashi T, Aoki I.
    • Journal Title

      J Pregnancy

      Volume: 1 Pages: 123717-123717

    • DOI

      10.1155/2011/123717

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Aberrant CD20 expression in angioimmunoblastic T-cell lymphoma2011

    • Author(s)
      Tachibana T, Tomita N, Furuya M, Yamanaka S, Takeuchi K, Nakamura N, Fujita H, Ishigatsubo Y
    • Journal Title

      Int Med

      Volume: 50 Pages: 495-499

    • NAID

      130000649867

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Birt-Hogg-Dubé (BHD)症候群の臨床病理学的検討2013

    • Author(s)
      古屋充子
    • Organizer
      第59回日本病理学会秋期特別総会
    • Place of Presentation
      甲府
    • Year and Date
      2013-11-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 多房性に発育したテストステロン産生性巨大性索間質性腫瘍の1例2013

    • Author(s)
      峰優子, 古屋充子ほか
    • Organizer
      第55回日本婦人科腫瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2013-07-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 骨盤リンパ節転移を伴ったUTROSCTと考えられる1例2013

    • Author(s)
      時長亜弥, 古屋充子ほか
    • Organizer
      第55回日本婦人科腫瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2013-07-21
    • Related Report
      2013 Final Research Report
  • [Presentation] Inflammatory microenvironm ent of endometriosis-associated ovarian cancer s suppressed CXCL4 and SOCS1 in the macr ophages2013

    • Author(s)
      古屋充子ほか
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] Novel mutation a nd distinctive clinicopathologic features in Asi an families with Birt-Hogg-Dubé syndrome2013

    • Author(s)
      中谷行雄, 古屋充子ほか
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] Japanese renal ce ll carcinoma patients with Birt-Hgg-Dubé syn drome : a putative hotspot, and pathway of ca rcinogenesis2013

    • Author(s)
      古賀俊輔, 古屋充子ほか
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] A clinicopathol ogic study of 72 individuals in 33Asian BHD families2013

    • Author(s)
      Furuya M, Tanaka R, et al
    • Organizer
      5^<th> BHD and 2^<nd> HLRCC Symposi um
    • Place of Presentation
      Paris
    • Related Report
      2013 Final Research Report
  • [Presentation] 子宮内膜症性関連卵巣癌における特異な炎症性微小環境の検討2013

    • Author(s)
      古屋充子, 古林直人ほか
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 遺伝性腎腫瘍に対する包括診療の取り組み2013

    • Author(s)
      古屋充子
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 気胸を有する多発性肺嚢胞の臨床病理学的検討2013

    • Author(s)
      古屋充子,田中玲子ほか
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 宮内膜症性関連卵巣癌における特異な炎症性微小環境の検討2013

    • Author(s)
      古屋充子, 古林直人, 宮城悦子, 長濱清隆, 宮城洋平, 長嶋洋治
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      ロイトン札幌 (北海道札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 遺伝性腎腫瘍に対する包括診療の取り組み-Birt-Hogg-Dubé症候群を中心に2013

    • Author(s)
      古屋充子
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      ロイトン札幌 (北海道札幌市)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 気胸を有する多発性肺嚢胞の臨床病理学的検討-Birt-Hogg-Dubé症候群を中心に2013

    • Author(s)
      古屋充子, 田中玲子, 長嶋洋治, 黒田直人, 中谷行雄
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      ロイトン札幌 (北海道札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 卵巣原発の腺扁平上皮癌の一例2013

    • Author(s)
      筒井美帆, 松村舞依, 三宅暁夫, 宇高直子, 古屋充子, 山中正二, 大橋健一, 稲山嘉明
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      ロイトン札幌 (北海道札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 微小内膜漿液腺癌(MUSC)の免疫組織化学的検討2013

    • Author(s)
      小野響子, 林宏行, 武居麻紀, 鈴木理絵, 立野正敏, 古屋充子
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      ロイトン札幌 (北海道札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 非定型的病理組織像を示した異時性腎癌および転移性肝癌の1例2013

    • Author(s)
      入部康弘, 古屋充子, 黒田直人, 加藤生真, 元井亨, 青木一郎, 長嶋洋治
    • Organizer
      第102回日本病理学会学術総会
    • Place of Presentation
      ロイトン札幌 (北海道札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 骨盤リンパ節転移を伴ったUterine tumor resembling ovarian sex cord tumor (UTROSCT)と考えられる1例2013

    • Author(s)
      時長亜弥,古屋充子,梅田茂明,中島泉,佐藤美紀子,長谷川哲哉,横田奈朋,沼崎令子,平原史樹, 宮城悦子
    • Organizer
      第55回日本婦人科腫瘍学会
    • Place of Presentation
      グランパシフィック (東京都港区)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 多房性に発育したテストステロン産生性巨大性索間質性腫瘍の1例2013

    • Author(s)
      峰優子,永田智子, 小野田登, 石川雅彦, 平原史樹, 古屋充子
    • Organizer
      第55回日本婦人科腫瘍学会
    • Place of Presentation
      グランパシフィック (東京都港区)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Inflammatory microenvironment of endometriosis-associated ovarian cancers suppressed CXCL4 and SOCS1 in the macrophages.2013

    • Author(s)
      古屋充子、古林直人、宮城悦子、宮城洋平
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Novel mutation and distinctive clinicopathologic features in Asian families with Birt-Hogg-Dubé syndrome2013

    • Author(s)
      中谷行雄, 古賀俊輔, 吉野一郎, 野村文雄, 長嶋洋治, 古屋充子
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Japanese renal cell carcinoma patients with Birt-Hgg-Dubé syndrome: a putative hotspot, and pathway of carcinogenesis.2013

    • Author(s)
      古賀俊輔、長嶋洋治、矢尾正祐、野村文雄、中谷行雄、古屋充子
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Birt-Hogg-Dubé (BHD) 症候群の臨床病理学的検討2013

    • Author(s)
      古屋充子
    • Organizer
      第59回日本病理学会秋期特別総会
    • Place of Presentation
      富士屋ホテル(山梨県甲府市)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Birt-Hogg-Dubé症候群に発生した甲状腺癌の1例2013

    • Author(s)
      松嶋惇,古屋充子,長嶋健,巣山貴仁,長嶋洋治,小野隆,太田聡,市川智彦,宮崎勝,中谷行雄
    • Organizer
      第59回日本病理学会秋期特別総会
    • Place of Presentation
      富士屋ホテル(山梨県甲府市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] A Clinicopathological Study of the Lung in 72 Individuals with Birt-Hogg-Dubé Syndrome2013

    • Author(s)
      Furuya M, Nakatani Y
    • Organizer
      Pulmonary Pathology Society Biennale Meeting
    • Place of Presentation
      Grenoble (France)
    • Related Report
      2013 Annual Research Report
  • [Presentation] A clinicopathologic study of 72 individuals in 33Asian BHD families.2013

    • Author(s)
      Furuya M, Tanaka R, Yao M, Nagashima Y, Koga S, Nakatani Y
    • Organizer
      5th BHD and 2nd HLRCC Symposium
    • Place of Presentation
      Paris (France)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Accelerated mTOR Signaling and Angiogenesis in the Pulmonary Cysts of Birt-Hogg-Dubé Syndrome.2012

    • Author(s)
      Nishii T, Tanabe M, Tanaka R, Matsuzawa T, Okudela K, Nozawa A, Nakatani Y, Furuya M
    • Organizer
      4th BHD Symposium 2012
    • Place of Presentation
      Cincinnati, OH(USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] A Clinicopathologic Study of Pulmonary Cysts in 11 BHD Families2012

    • Author(s)
      Koga S, Furuya M, Tanaka R,Matsuzawa T, Nagashima Y, Nakatani Y
    • Organizer
      4th BHD Symposium 2012
    • Place of Presentation
      Cincinnati, OH(USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] Birt-Hogg-Dube症候群と確定した4家系における多発性肺嚢胞の病理学的特徴2011

    • Author(s)
      古屋充子、古賀俊輔、田中玲子,山口学、吉野一郎,谷田部恭,黒田直人、後藤田裕子,長嶋洋治,廣島健三,野村文夫,青木一郎、中谷行雄
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Research-status Report
  • [Presentation] CXCケモカイン軸に特徴づけられる炎症性微小環境の変化2011

    • Author(s)
      古屋充子、米山朋那,宮城悦子,上大介,長濱清隆、田中玲子,太田一郎,宮城洋平,長嶋洋治,平原史樹,稲山嘉明,青木一郎
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Research-status Report
  • [Presentation] Differential expression of CXCR3 variants and corresponding CXC chemokines in ovarian cancers and endometriosis.2011

    • Author(s)
      古屋充子,宮城悦子,上大介,宮城洋平,平原史樹,長嶋洋治、稲山嘉明,青木一郎
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Research-status Report
  • [Presentation] Analysis of lung cysts in Birt-Hogg-Dube syndrome: pathological features and expression of mTOR signaling molecules.2011

    • Author(s)
      古賀俊輔,古屋充子,吉野一郎,野村文夫,谷田部恭,長嶋洋治,廣島健三,青木一郎、中谷行雄
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Research-status Report
  • [Presentation] 急激な経過を辿った骨盤内巨大腫瘍の1剖検例2011

    • Author(s)
      北山玲子、長濱清隆、高見美緒、村瀬真理子、丸山康世、佐藤美紀子、宮城悦子、平原史樹、山中 正二、稲山嘉明、古屋充子
    • Organizer
      第34回日本婦人科病理学会
    • Place of Presentation
      杏林大学(東京)
    • Related Report
      2011 Research-status Report
  • [Presentation] 新規遺伝子変異を示したBirt-Hogg-Dubé症候群の1例:反復性桔梗を伴う多発性肺嚢胞の分子病理学的検討.

    • Author(s)
      西井鉄平,田辺美樹子,奥寺康司,田中玲子,松澤哲宏,野澤昭典,中谷行雄,古屋充子
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 子宮内膜症関連卵巣癌における炎症性微小環境の検討.

    • Author(s)
      古屋充子,宮城悦子,長濱清隆,宮城洋平,長嶋洋治,平原史樹,稲山嘉明,青木一郎
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] Birt-Hogg-Dube症候群と確定した10家系における肺嚢胞の病理学的検討.

    • Author(s)
      古屋充子,田中玲子、谷田部恭、藤井丈士,後藤田裕子,黒田直人,森谷鈴子,古賀俊輔,長濱清隆,長嶋洋治,長谷川剛,廣島健三,中谷行雄
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] Synchronous and multifocal mucinous lesions involving the female genital tractの一例.

    • Author(s)
      長濱清隆,中山崇,山中正二,古屋充子
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 組織型診断に苦慮した卵巣未熟奇形腫肺転移の一例.

    • Author(s)
      三宅暁夫,松村舞依,岡田千尋,宇髙直子,山中正二,中山崇,古屋充子,稲山嘉明,大橋健一
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 卵巣成熟奇形腫に悪性黒色腫を合併した一例.

    • Author(s)
      岡田千尋,中山崇,松村舞依,三宅暁夫,宇髙直子,山中正二,古屋充子,稲山嘉明,大橋健一
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 子宮筋層に限局した原発巣でありながら横行結腸転移をきたした低悪性度子宮内膜間質肉腫の1例,

    • Author(s)
      時長亜弥,佐藤美紀子,古屋充子,長谷川哲哉,宇髙直子,新野史,沼崎令子,宮城悦子,山中正二,平原史樹
    • Organizer
      第52回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] Pathology of Pulmonary Cysts in Birt-Hogg-Dubé syndrome: Impact on Diagnosis of BHD Families with Renal Cell Cancers.

    • Author(s)
      中谷行雄, 古賀俊輔, 吉野一郎, 野村文夫, 長嶋洋治, 古屋充子
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Related Report
      2012 Research-status Report
  • [Presentation] Deranged balance of CXC chemokines and CXCR3 variants in endometriosis-associated ovarian cancers.

    • Author(s)
      古屋充子,宮城悦子,平原史樹,宮城洋平,稲山嘉明,青木一郎
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Related Report
      2012 Research-status Report
  • [Presentation] Genetic Testing, Clinicopathologic Findings and Care of Renal Cell Cancers in the Patients with Birt-Hogg-Dubé Syndrome.

    • Author(s)
      古賀俊輔, 長嶋洋治, 矢尾正祐, 野村文夫, 中谷行雄, 古屋充子
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Related Report
      2012 Research-status Report
  • [Book] Nova Science Publishers. Pneumothorax2013

    • Author(s)
      Furuya M, Nakatani Y
    • Publisher
      Classification, Treatment and Prognostic Factors
    • Related Report
      2013 Final Research Report
  • [Book] Pneumothorax: Classification, Treatment and Prognostic Factors.2013

    • Author(s)
      Furuya M and Nakatani Y
    • Total Pages
      142
    • Publisher
      Nova Science Publishers.
    • Related Report
      2013 Annual Research Report
  • [Book] 腫瘍鑑別アトラス「腎癌」2013

    • Author(s)
      古屋充子
    • Total Pages
      253
    • Publisher
      文光堂
    • Related Report
      2013 Annual Research Report
  • [Remarks]

    • URL

      http://www-user.yokohama-cu.ac.jp/~byori2/index.html

    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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