| Project/Area Number |
23591143
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Shinshu University |
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Principal Investigator |
KUBO Keishi 信州大学, 医学部, 特任教授 (80143965)
|
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| Co-Investigator(Kenkyū-buntansha) |
HANAOKA Masayuki 信州大学, 医学部, 教授 (20334899)
OTA Masao 信州大学, 医学部, 准教授 (50115333)
ITO Michiko 信州大学, 医学部附属病院, 助教 (60569812)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 遺伝子 / ゲノム / 薬剤性肺障害 / 遺伝子多型 / 単塩基多型 / ＨＬＡ解析 / HLA解析 / GWAS解析 |
|---|
| Research Abstract |
In this study, we investigated genetic background in patients with drug-induced lung disease, which has displayed an increasing trend in recent years. Upon considering gene polymorphism in patients with drug-induced lung disease for the purpose of early diagnosis, there were multiple relationships between gene polymorphism and the disease. Going forward, by means of the accumulation of an additional number of cases and genetic functional analysis, an even clearer understanding of the clinical conditions of drug-induced lung damage can be expected.
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