Preparations for optimal glycemic management in acute ischemic stroke patients: NCVC stroke registry
Project/Area Number |
23591289
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Neurology
|
Research Institution | National Cardiovascular Center Research Institute |
Principal Investigator |
ARIHIRO SHOJI 独立行政法人国立循環器病研究センター, 病院, 医師 (10599723)
|
Co-Investigator(Kenkyū-buntansha) |
TOYODA Kazunori 国立循環器病研究センター, 病院, 部長 (50275450)
|
Co-Investigator(Renkei-kenkyūsha) |
KOGA Masatoshi 国立循環器病研究センター, 病院, 医長 (30512230)
|
Project Period (FY) |
2011-04-28 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 糖尿病 / 脳梗塞 / 脳血管障害 |
Outline of Final Research Achievements |
We investigated retrospectively 1351 consecutive acute ischemic stroke (AIS) patients from the NCVC stroke registry, and 29% of them had diabetes mellitus (DM). Of these stroke patients with DM, less than 4% had received intravenous tissue plasminogen activator (tPA), and neurological deteriorations were more frequently observed. DM and atrial fibrillation (AF) were independently associated with poor functional outcomes at discharge and 3months, after multivariable logistic regression analysis adjusting tPA therapy. In AIS patients with DM, patients having AF, prior diabetic medication and severe neurological deficits, often received sliding scale insulin therapy (SSIT). These patients with SSIT had more neurological improvements, compared with those without SSIT, whereas hypoglycemic (<= 80 mg/dl) episodes were also found in 15% of them. We need to take care about setting SSIT for prior diabetic medication users.
|
Report
(5 results)
Research Products
(16 results)
-
[Journal Article] Blood glucose levels during the initial 72 h and 3-month functional outcomes in acute intracerebral hemorrhage: the SAMURAI-ICH study.2015
Author(s)
Koga M, Yamagami H, Okuda S, Okada Y, Kimura K, Shiokawa Y, Nakagawara J, Furui E, Hasegawa Y, Kario K, Arihiro S, Sato S, Homma K, Matsuki T, Kinoshita N, Nagatsuka K, Minematsu K, Toyoda K; SAMURAI Study Investigators.
-
Journal Title
J Neurol Sci.
Volume: 350
Issue: 1-2
Pages: 75-78
DOI
Related Report
Peer Reviewed
-
[Journal Article] Trends in oral anticoagulant choice for acute stroke patients with nonvalvular atrial fibrillation in Japan: The SAMURAI-NVAF Study.2015
Author(s)
Toyoda K, Arihiro S, Todo K, Yamagami H, Kimura K, Furui E, Terasaki T, Shiokawa Y, Kamiyama K, Takizawa S, Okuda S, Okada Y, Kameda T, Nagakane Y, Hasegawa Y, Mochizuki H, Ito Y, Nakashima T, Takamatsu K, Nishiyama K, Kario K, Sato S, Koga M; SAMURAI Study Investigators.
-
Journal Title
Int J Stroke.
Volume: [Epub ahead of print]
Issue: 6
Pages: 836-842
DOI
Related Report
Peer Reviewed
-
-
-
-
[Presentation] Three-month Outcomes in Japanese Stroke /TIA Patients With Non-Valvular Atrial Fibrillation After Initiating Oral Anticoagulants2015
Author(s)
Shoji Arihiro, Kenichi Todo, Masatoshi Koga, Hiroshi Yamagami,Tadashi Terasaki, , Kazumi Kimura, Yoshiaki Shiokawa, Kenji Kamiyama, Shunya Takizawa, Yasushi Okada, Yasuhiro Hasegawa, Satoshi Okuda, Hiroshi Mochizuki , Yasuhiro Ito, Takahiro Nakashima, Tomoaki Kameda, Yoshinari Nagakane, Kazunori Toyoda, et al.
Organizer
International Stroke Conference
Place of Presentation
Nashville
Year and Date
2015-02-11 – 2015-02-13
Related Report
-
-
-
-
-
-
-
-
-
-